5fluorouridine

5-Fluorouridine is a metabolite of 5-fluorouracil that inhibits rRNA synthesis in human colon cancer cells and exhibits antitumor and antiviral activity. 5-Fluorouridine exerts a cytotoxic effect on the growth of L1210 cells, with an IC₅₀ value of 2 nM. 5-Fluorouridine binds to poly-A RNA and exhibits antiproliferative activity. 5-Fluorouridine can be used in studies of nucleic acid metabolism, cancer chemotherapy, and viral replication mechanisms.

5-Fluorouridine 5'-O-β-D-galactopyranoside (also known as 5'-O-β-D-galactosyl-5-fluorouridine) is a prodrug of 5-Fluorouridine. It can be enzymatically converted by β-D-galactosidase into 5-Fluorouridine, a highly effective antineoplastic agent.

5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.

5'(R)-C-Methyl-5-fluorouridine, a uridine analogue, potentially exhibits antiepileptic properties. Its analogues play a crucial role in researching anticonvulsant and anxiolytic effects and are essential in developing new antihypertensive agents [1].

3'-Deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-Modified nucleoside.

Nucleoside Derivatives - Azido-nucleosides, 3'-Modified nucleosides, 5-Modified pyrimidine nucleosides; Fluoro-modified nucleosides

Nucleoside Derivatives - 5'-Modified nucleosides, 5-Modified pyrimidine nucleosides, Fluoro-modified nucleosides

3'-Deoxy-3'-a-C-methyl-5-fluorouridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside, Fluoro-modified nucleoside.

Nucleoside Derivatives - Amino-nucleosides, 3'-Modified nucleosides, Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides

Nucleoside Derivatives - 3'-Deoxy nucleosides, 5-Modified pyrimidine nucleosides, Fluoro-modified nucleosides

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-Modified nucleoside.

5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluoro-uridine is a Nucleoside Derivative - Didehydro-nucleoside; Fluoro-modified nucleoside.

Nucleoside Derivatives - 2',3'-Dideoxy-nucleoside; Fluoro-modified nucleoside

2',3'-Dideoxy-2',3'-didehydro-5-fluoro-uridine is a Nucleoside Derivative - Didehydro-nucleoside; Fluoro-modified nucleoside.

2'-Deoxy-5-Fluorouridine 5'-phosphate triethyl ammonium salt is a valuable organic compound for life sciences research (catalog number TNU1203, CAS number 134-46-3).

Nucleoside Derivatives - Halo-nucleoside; 5-modified nucleosides; 2'-Modified nucleosides; Fluoro-modified nucleosides

Nucleoside Derivatives - 3'-Modified nucleosides, Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides

5-F-UTP (5-Fluorouridine-5'-triphosphate) is a monomeric raw material used in nucleic acid synthesis.