22:0 trehalose

Trehalose-6,6'-dibehenate, a bioactive glycolipid, is applicable for the preparation of vaccine adjuvant [1].

Guanidylfungin A is a useful organic compound for research related to life sciences. The catalog number is T123899 and the CAS number is 94116-22-0.

Chagreslactone is a useful organic compound for research related to life sciences. The catalog number is T124201 and the CAS number is 799269-22-0.

Gibberellin A14 is a useful organic compound for research related to life sciences. The catalog number is T124777 and the CAS number is 4955-22-0.

BE 52440A is a natural product that can be used as a reference standard. The CAS number of BE 52440A is 195051-22-0.

1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound utilized in the preparation of liposomes. Liposomes, forming the central component of concentric phospholipid bilayer vesicles, are pivotal in constructing drug delivery systems for anti-cancer and anti-infection applications. They effectively encapsulate hydrophilic payloads within their aqueous internal spaces, while lipophilic compounds are integrated into and become part of the lipid bilayer. This compound is particularly effective for delivering antisense oligonucleotides, addressing challenges such as inefficient cellular uptake and rapid loss in the body.

1,3-Didocosahexaenoyl glycerol (DG(22:6 0:0 22:6)) is an ω-3 polyunsaturated fatty acid that exhibits cardioprotective effects in a rat myocardial ischemia reperfusion (I R) injury model through its interaction with Poly-l-glutamic acid (PGA).

C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyelin levels are decreased in T-47D mammary epithelial cells and increased in MDA-MB-231 breast cancer cells relative to C16 sphingomyelin .

C22 Ceramide (d18:1 22:0) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isolated rat liver mitochondria and liposomes.

3-hydroxy Docosanoic acid is a hydroxylated form of the 22-carbon saturated docosanoic acid . It is found in lipopolysaccharides from C. trachomatis and C. psittaci and in S. synnaedendra. 3-hydroxy Docosanoic acid, in the form of an acyl-CoA metabolite, is an intermediate in fatty acid chain elongation from arachidic acid to docosanoic acid (C22:0).

C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C22 dihydro 1-Deoxyceramide (m18:0/22:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found as the most prevalent dihydro deoxyceramide species in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4 |1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemical structure of native 1-deoxysphingosine. J. Lipid Res. 57(7), 1194-1203 (2016).|2. Alecu, I., Othman, A., Penno, A., et al. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. J. Lipid Res. 58(1), 60-71 (2017).|3. Alecu, I., Tedeschi, A., Behler, N., et al. Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction. J. Lipid. Res. 58(1), 42-59 (2017).|4. Schwartz, N.U., Mileva, I., Gurevich, M., et al. Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue. Prostaglandins Other Lipid Mediat. 141, 40-48 (2019).

C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system.1,2C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricted diet.1C22 Galactosylceramide has been found in postmortem hippocampus from patients with Alzheimer's disease.2[Matreya, LLC.]

C22 Glucosylceramide (d18:1/22:0) is an endogenous glucosylceramide. Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide , as well as oligoglycolipids and gangliosides. Phospholipase A2 (PLA2) type XIIA knockdown increases C22 glucosylceramide (d18:1/22:0) expression in rat brain. It is also increased in the brain, but not the liver or spinal cord, of mice fed a methionine-restricted diet. In human athletes, plasma levels of C22 glucosylceramide (d18:1/22:0) increase during exercise and return to basal levels during recovery. This product contains C22 glucosylceramide (d18:1/22:0) isolated from bovine buttermilk.

(Tosylazanediyl)bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) is a useful organic compound for research related to life sciences. The catalog number is T65339 and the CAS number is 16695-22-0.

(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66549 and the CAS number is 521284-22-0.

1-Stearoyl-2-docosahexaenoyl-sn-glycerol (18:0-22:6 DG) is a diacylglycerol capable of binding to RasGRP and modulating the activation of MAP kinases.

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) acts as a cyclin-dependent kinase (CDK) inhibitor, promoting apoptosis and restricting the proliferation of various cancer cell lines [1].

C22 Phytoceramide (t18:0 22:0) is a lipid molecule that can be used in life science related research. The CAS number of C22 Phytoceramide (t18:0 22:0) is 164576-03-8.

1,3-Didocosanoyl-2-oleoyl glycerol, a triacylglycerol, incorporates docosanoic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. Present in cocoa butter, its use as a seed material in dark chocolate enhances solidification rates and inhibits fat bloom formation.

C6 Biotin Glucosylceramide (d18:1 6:0) is a lipid molecule that can be used in life science related research. The CAS number of C6 Biotin Glucosylceramide (d18:1 6:0) is 2692623-22-4.

1,2-Didocosanoyl-3-myristoyl-rac-glycerol, a triacylglycerol, features docosanoic acid at both the sn-1 and sn-2 positions, and myristic acid at the sn-3 position.

1,3-Dipalmitoyl-2-docosahexaenoyl glycerol, a triacylglycerol, features palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. Its dietary administration (30 g/kg) has been shown to decrease hepatic triglyceride and cholesterol levels in mice.

1-Myristoyl-3-docosanoyl-rac-glycerol is a diacylglycerol with myristic acid at the sn-1 position and docosanoic acid at the sn-3 position.

DSPE-PEG-Maleimide features DSPE phospholipids and maleimide for the preparation of nano-structured lipid carriers. It enhances the stability of encapsulated active molecules and prolongs circulation time in the bloodstream.