2-chloroacetamide

2-Chloroacetamide is a versatile chemical compound with several applications. Acting as a preservative and herbicide, it effectively controls vegetation in upland areas as well as paddy fields. Additionally, it serves as a biocide in diverse sectors including agriculture, glues, paints, and coatings. Notably, 2-Chloroacetamide demonstrates inhibitory properties toward very-long-chain fatty acid elongase, further highlighting its multifaceted nature.

5-(2-Chloroacetamide) thalidomide is an analog of Thalidomide. Thalidomide functions by recruiting E3 ligase for ubiquitination, leading to the degradation of specific proteins. This compound features a chloroacetamide moiety, which acts as a thiol-specific reactive group.

N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a useful organic compound for research related to life sciences and the catalog number is T65965.

N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline (KM1954) is an insecticide, it is most active against 1st stage Ae. aegypti larvae with LC50 values of 125μM.

MurA-IN-2 (compound 37), a potent MurA inhibitor featuring a chloroacetamide fragment with a primary aliphatic amine, exhibits antibacterial activity by inhibiting bacterial cell wall synthesis, with an IC50 of 39 μM [1].

SARS-CoV-2-IN-75 (compound 13), a chloroacetamide-based inhibitor, effectively suppresses cellular replication of SARS-CoV-2. It achieves a half-log reduction in viral titer (EC 68) at a concentration of 3 μM [1].