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1973485-06-1

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JAK-IN-14
T97641973485-06-1
JAK-IN-14 (compound 16) is a specific JAK1 inhibitor with IC50<5 μM. It prevents JAK1 phosphorylation by binding to the active site of JAK1, and is more than 8-fold selective for JAK1 over JAK2 JAK3, and can be used in immune, inflammation and cancer research.
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6-8 weeks
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