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18000-24-3

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  • Inhibitors & Agonists
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7-Chlorokynurenic acid
7-CKA, 7-chloro-4-hydroxy-2-carboxyquinoline
T10191L18000-24-3In house
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
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4-6 weeks
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TargetMol
7-Chlorokynurenic acid sodium salt
7-CKA sodium salt
T101911263094-00-3
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM) and a potent inhibitor of the reuptake of glutamate into synaptic vesicles (Ki: 0.59 μM).
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1-2 weeks
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