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By Target- Apoptosis
- Autophagy(1)
- LPL Receptor(1)
- S1P Receptor(1)
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Results for "
1415562-82-1
" in TargetMol Product Catalog- Inhibitors & Agonists1
PF-543
Cited
Sphingosine Kinase 1 Inhibitor II, PF 543
T60851415562-82-1
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 of 2.0 nM and Ki of 3.6 nM.
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Cited
PF-543 HCL
T88401706522-79-3
PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
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CitedSphingosine Kinase 1 Inhibitor II Citrate, PF543 Citrate
T124361415562-83-2
PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate) is a selective and potent inhibitor of sphingosine kinase 1 (SPHK1) and is an efficient inhibitor of 1-phosphate sphingosine (S1P) formation. It possesses anticancer, antifibrotic, and anti-inflammatory activities and can be used in research on colorectal cancer.
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