126454-22-6

(R)-(+)-Anatabine, the less active R-enantiomer of Anatabine, is a potent agonist of α4β2 nAChR.

Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tart

(R,S)-Anatabine is a minor tobacco alkaloid found in the Solanaceae family of plants, and serves as a specific marker for detecting tobacco use.

Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in hum

Anatabine dicitrate, a tobacco alkaloid that can cross the blood-brain barrier, is a potent α4β2 nAChR agonist and inhibits NF-κB activation, thereby reducing amyloid-β (Aβ) production by preventing β-cleavage of the amyloid precursor protein.