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1169558-38-6

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
XL413
T33521169558-38-6In house
XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induct
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4-6 weeks
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TargetMol | Citations Cited
TargetMol
XL413 hydrochloride
BMS-863233 Hydrochloride
T67352062200-97-7
XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC 50 of 3.4 nM. XL413 hydrochloride also exhibits potent effect with IC 50 s of 215, 42 nM on CK2, PIM1, respectively, and an EC 50 of 118 nM on pMCM.
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6-8 weeks
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