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Results for "
α hydroxytamoxifen
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products1
α-Hydroxytamoxifen
(E)-α-Hydroxy tamoxifen, α-OHTAM
T1919297151-02-5
α-Hydroxytamoxifen, a metabolite of tamoxifen, reacts with DNA and forms DNA adducts.
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SNIPER(ER)-87
T186972222354-91-6
SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (ERα) ligand 4-hydroxytamoxifen using a PEG linker. It effectively degrades the ERα protein with an IC50 value of 0.097 μM. Within cells, SNIPER(ER)-87 selectively recruits XIAP to ERα, and XIAP functions as the primary E3 ubiquitin ligase responsible for the degradation of ERα induced by SNIPER(ER)-87[1][2].
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