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(s)()5iodowillardiine
" in TargetMol Product Catalog- Inhibitors & Agonists1
5-Iodowillardiine
(S)-5-Iodowillardiine
T23295140187-25-3
5-Iodowillardiine is a selective agonist for specific kainate receptor subunits that robustly activates GluK1 (GluR5) and GluK5 (KA2)-containing receptors while displaying minimal activity at AMPA receptors and no measurable agonism toward GluK2 (GluR6) subunits. Despite its excitotoxic neurotoxic activity in vivo, 5-Iodowillardiine remains a powerful experimental tool for dissecting kainate receptor subtype distribution, synaptic function, and excitatory neurotransmission in the brain and spinal cord.
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