Virus Protease

Virus protease or 3C protease are virus cysteine proteases which have essential role in viral replication. The protease cleaves the precursor viral polyprotein to produce functional proteins and enzymes.Virus proteases are attractive target for therapeutic agents for treatment of diseases caused by the common cold virus.Viral protease - a Cys protease fold is similar to that of trypsin-like serine proteases. The active site triad contains Cys147, His40 and Glu71 (PDB entry 1cqq).

Cat. No.	Product name	CAS No.	Purity
T5158	N-Desmethylclozapine	6104-71-8	98.45%
T5158	N-Desmethylclozapine is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist a...
T2244	ESI-09	263707-16-0	98.48%
T2244	ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.
T1307	Carmofur	61422-45-5	98.59%
T1307	Carmofur is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopat...
T8328	STING agonist-1	702662-50-8	98.76%
T8328	STING agonist-1 is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
T12711	Retro-2 cycl	1429192-00-6	98.82%
T12711	Retro-2 cycl is a dihydroquinazolinone (DHQZ) retrograde trafficking inhibitor. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus(IC50s of 54 μM and 1...
T4S0999	(2S)-Isoxanthohumol	70872-29-6	98.82%
T4S0999	1. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol wi...
T2432	PD 169316	152121-53-4	98.83%
T2432	PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.
T8205	Norwogonin	4443-09-8	98.84%
T8205	Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).
T11281L	FGI-106 tetrahydrochloride	1149348-10-6	98.98%
T11281L	FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetra...
T4492	Pocapavir	146949-21-5	99.01%
T4492	Pocapavir is an investigational enterovirus (EV) capsid inhibitor.
T0800	Danthron	117-10-2	99.03%
T0800	Danthron is a natural product, regulates glucose, and lipid metabolism by activating AMPK.
T3759	3,4-Dimethoxycinnamic acid	2316-26-9	99.07%
T3759	3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer found in Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effect...
T0005	Aspirin	50-78-2	99.09%
T0005	Acetylsalicylic acid is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Acetylsalicyl...
T8498	EIDD-1931	3258-02-4	99.14%
T8498	EiDD1931 is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells,...
T1776	Plerixafor	110078-46-1	99.17%
T1776	Plerixafor, a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
T0495	Aminothiazole	96-50-4	99.18%
T0495	Aminothiazole, a thyroid inhibitor, displays antibacterial activity.
TMO2787	Anthraquinone	84-65-1	99.2%
TMO2787	Anthraquinones are the main active constituents in herbs often used to relieve constipation.
T0122	Bergenin	477-90-7	99.43%
T0122	Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
T1717	Alpha-Mangostin	6147-11-1	99.49%
T1717	Mangostin is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
TN2111	Prunin	529-55-5	99.52%
TN2111	Prunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-re...