TNF

Tumor necrosis factor (TNF, cachexin, or cachectin; once named as tumor necrosis factor alpha or TNFα) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNF is a member of the TNF superfamily, consisting of various transmembrane proteins with a homologous TNF domain.

Cat. No.	Product name	CAS No.	Purity
T1265	Amrinone	60719-84-8	99.86%
T1265	Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.
T0694	Pranlukast	103177-37-3	99.85%
T0694	Pranlukast (ONO-1078) is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic ...
T5788	XYLOBIOSE	6860-47-5	99.84%
T5788	XYLOBIOSE ia a natural product,and exhibited therapeutic potential for treating obesity which involved suppression of fat deposition and obesity-related metaboli...
TN3609	Catalposide	6736-85-2	99.82%
TN3609	Catalposide is a potent inducer of (HO)-1 isolated from Catalpa ovate G. Don (Bignoniaceae). Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, a...
TN1295	5-O-Caffeoylshikimic acid	73263-62-4	99.82%
TN1295	5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of...
T2065	Bioymifi	1420071-30-2	99.79%
T2065	Bioymifi (DR5 Activator) is a novel and potent small-molecule activator of the TRAIL receptor DR5 in human cancer cells.
T3770	Taraxasterol	1059-14-9	99.79%
T3770	Taraxasterol (Taraxasterin) is compound with anti-inflammatory activity.
T2993	Cordycepin	73-03-0	99.78%
T2993	Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic ac...
T2932	Ginsenoside Rh1	63223-86-9	99.77%
T2932	Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T2794	Astilbin	29838-67-3	99.76%
T2794	Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.
T2S0501	Ilexgenin A	108524-94-3	99.75%
T2S0501	Ilexgenin A is a novel pentacyclic triterpenoid, is a compound extracted from leaves of Ilex hainanensis Merr
T0131	Cepharanthine	481-49-2	99.74%
T0131	Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and ...
TN1742	Homovanillyl alcohol	2380-78-1	99.74%
TN1742	Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homo...
T6S1538	Neochlorogenic acid	906-33-2	99.73%
T6S1538	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
T26326	VU0285655-1	1158347-73-9	99.73%
T26326	VU0285655-1(BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhib...
TN1936	Mogroside III-E	88901-37-5	99.73%
TN1936	Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in...
TQ0181	Resatorvid	243984-11-4	99.73%
TQ0181	Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid binds directly to Cys747 and prevents TLR4 from binding to TIRAP, thereb...
T5S0993	Kurarinone	34981-26-5	99.72%
T5S0993	Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong ...
T7001	TIC10	1616632-77-9	99.72%
T7001	TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior sta...
T0429	Glucosamine	3416-24-8	99.72%
T0429	Glucosamine (Chitosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Supplemental glucosamine ...