T6S2140 |
β-Anhydroicaritin
|
38226-86-7
|
96.95%
|
|
1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turn...
|
T3893 |
Forsythoside B
|
81525-13-5
|
96.52%
|
|
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response an...
|
TN3849 |
Dihydrodehydrodiconiferyl alcohol
|
28199-69-1
|
96.50%
|
|
Dihydrodehydrodiconiferyl alcohol is the methanolic extract of Liriodendron tulipifera[1].
|
TN1511 |
Cleomiscosin A
|
76948-72-6
|
100.00%
|
|
Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin ...
|
T7889 |
C25-140
|
1358099-18-9
|
100%
|
|
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.
|
T22922 |
Lenalidomide hemihydrate
|
847871-99-2
|
100%
|
|
Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage bind...
|
TJS1779 |
Protosappanin A
|
102036-28-2
|
100%
|
|
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inf...
|
T0875 |
Acetylcysteine
|
616-91-1
|
100%
|
|
Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus th...
|
T11484 |
GSK2593074A
|
1337531-06-2
|
100%
|
|
GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.
|
T4319 |
Hispidol
|
5786-54-9
|
100%
|
|
Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelia...
|
T5785 |
MALTOTETRAOSE
|
34612-38-9
|
|
|
Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in th...
|
T3280 |
Clodronate disodium tetrahydrate
|
88416-50-6
|
|
|
Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.
|
TN1983 |
Neoisoastilbin
|
54141-72-9
|
|
|
Neoisoastilbin may have antioxidant and anti-inflammatory activities.
|
T2893 |
Muscone
|
541-91-3
|
|
|
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
|
T83628 |
TNF/IFNγ-IN-1
|
876013-29-5
|
98%
|
|
TNF/IFNγ-IN-1 (TGA) is a dual inhibitor of TNF and IFN-γ. TNF/IFNγ-IN-1 has potential antioxidant and anti-inflammatory activities for neurodegenerative diseases...
|
T4637 |
R-7050
|
303997-35-5
|
98%
|
|
R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.
|
TQ0218 |
Deoxyandrographolide
|
79233-15-1
|
98%
|
|
Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory media...
|
TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
T12985 |
SPD304 dihydrochloride
|
1049741-03-8
|
98%
|
|
SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
|
TN1599 |
Eburicoic acid
|
560-66-7
|
98%
|
|
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in...
|