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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Cat. No. Product name CAS No. Purity Chemical Structure
T7066 Fosphenytoin disodium 92134-98-0 99.91%
Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
T1073 Dronedarone hydrochloride 141625-93-6 99.91%
Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
T0044 Oxethazaine 126-27-2 99.92%
Oxethazaine, a topical anesthetic, is used to prevent acid-induced esophageal pain.
T6566 Levobupivacaine hydrochloride 27262-48-2 99.93%
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...
T0207 Ranolazine dihydrochloride 95635-56-6 99.93%
Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and...
T5S0890 Oleandrin 465-16-7 99.94%
1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional lev...
T4490 PF-01247324 875051-72-2 99.94%
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
T0267 Zonisamide 68291-97-4 99.94%
Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydra...
T0008 Phenytoin sodium 630-93-3 99.95%
Phenytoin sodium is an inactive stabilizer for voltage-gated sodium channel .
T0939 Phenytoin 57-41-0 99.95%
Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux fr...
T7811 Pilsicainide HCl 88069-49-2 99.96%
Pilsicainide HCl is a pure sodium channel blocker
TN1740 Homoeriodictyol 446-71-9 99.96%
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
T0924 Benzocaine 94-09-7 99.97%
Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
T0470 Nefopam hydrochloride 23327-57-3 99.97%
Nefopam Hydrochloride is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
T5319 Rimeporide 187870-78-6 99.98%
Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
T9461 AZ194 2241651-99-8 98%
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
T27794 λ-Cyhalothrin 91465-08-6 98%
lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. lambda-Cyhalothrin is used to control ...
T3021 Bulleyaconitine A 107668-79-1 98%
Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
TN5141 Thevetin B 27127-79-3 98%
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
T4699 5-(N,N-Hexamethylene)-amiloride 1428-95-1 85.48%
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-...
Fosphenytoin disodium
T7066
Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
Dronedarone hydrochloride
T1073
Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
Oxethazaine
T0044
Oxethazaine, a topical anesthetic, is used to prevent acid-induced esophageal pain.
Levobupivacaine hydrochloride
T6566
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...
Ranolazine dihydrochloride
T0207
Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and...
Oleandrin
T5S0890
1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional lev...
PF-01247324
T4490
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
Zonisamide
T0267
Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydra...
Phenytoin sodium
T0008
Phenytoin sodium is an inactive stabilizer for voltage-gated sodium channel .
Phenytoin
T0939
Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux fr...
Pilsicainide HCl
T7811
Pilsicainide HCl is a pure sodium channel blocker
Homoeriodictyol
TN1740
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
Benzocaine
T0924
Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
Nefopam hydrochloride
T0470
Nefopam Hydrochloride is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
Rimeporide
T5319
Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
AZ194
T9461
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
λ-Cyhalothrin
T27794
lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. lambda-Cyhalothrin is used to control ...
Bulleyaconitine A
T3021
Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
Thevetin B
TN5141
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
5-(N,N-Hexamethylene)-amiloride
T4699
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-...
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