Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.

Cat. No.	Product name	CAS No.	Purity
T7066	Fosphenytoin disodium	92134-98-0	99.91%
Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
T1073	Dronedarone hydrochloride	141625-93-6	99.91%
Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
T0044	Oxethazaine	126-27-2	99.92%
Oxethazaine, a topical anesthetic, is used to prevent acid-induced esophageal pain.
T6566	Levobupivacaine hydrochloride	27262-48-2	99.93%
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...
T0207	Ranolazine dihydrochloride	95635-56-6	99.93%
Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and...
T5S0890	Oleandrin	465-16-7	99.94%
1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional lev...
T4490	PF-01247324	875051-72-2	99.94%
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
T0267	Zonisamide	68291-97-4	99.94%
Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydra...
T0008	Phenytoin sodium	630-93-3	99.95%
Phenytoin sodium is an inactive stabilizer for voltage-gated sodium channel .
T0939	Phenytoin	57-41-0	99.95%
Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux fr...
T7811	Pilsicainide HCl	88069-49-2	99.96%
Pilsicainide HCl is a pure sodium channel blocker
TN1740	Homoeriodictyol	446-71-9	99.96%
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
T0924	Benzocaine	94-09-7	99.97%
Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
T0470	Nefopam hydrochloride	23327-57-3	99.97%
Nefopam Hydrochloride is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
T5319	Rimeporide	187870-78-6	99.98%
Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
T9461	AZ194	2241651-99-8	98%
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
T27794	λ-Cyhalothrin	91465-08-6	98%
lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. lambda-Cyhalothrin is used to control ...
T3021	Bulleyaconitine A	107668-79-1	98%
Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
TN5141	Thevetin B	27127-79-3	98%
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
T4699	5-(N,N-Hexamethylene)-amiloride	1428-95-1	85.48%
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-...

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T7066

Fosphenytoin disodium

92134-98-0

99.91%

Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

T1073

Dronedarone hydrochloride

141625-93-6

99.91%

Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.

T0044

Oxethazaine

126-27-2

99.92%

Oxethazaine, a topical anesthetic, is used to prevent acid-induced esophageal pain.

T6566

Levobupivacaine hydrochloride

27262-48-2

99.93%

Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...

T0207

Ranolazine dihydrochloride

95635-56-6

99.93%

Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and...

T5S0890

Oleandrin

465-16-7

99.94%

1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional lev...

T4490

PF-01247324

875051-72-2

99.94%

PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).

T0267

Zonisamide

68291-97-4

99.94%

Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydra...

T0008

Phenytoin sodium

630-93-3

99.95%

Phenytoin sodium is an inactive stabilizer for voltage-gated sodium channel .

T0939

Phenytoin

57-41-0

99.95%

Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux fr...

T7811

Pilsicainide HCl

88069-49-2

99.96%

Pilsicainide HCl is a pure sodium channel blocker

TN1740

Homoeriodictyol

446-71-9

99.96%

Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...

T0924

Benzocaine

94-09-7

99.97%

Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

T0470

Nefopam hydrochloride

23327-57-3

99.97%

Nefopam Hydrochloride is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.

T5319

Rimeporide

187870-78-6

99.98%

Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.

T9461

AZ194

2241651-99-8

98%

CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.

T27794

λ-Cyhalothrin

91465-08-6

98%

lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. lambda-Cyhalothrin is used to control ...

T3021

Bulleyaconitine A

107668-79-1

98%

Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.

TN5141

Thevetin B

27127-79-3

98%

Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.

T4699

5-(N,N-Hexamethylene)-amiloride

1428-95-1

85.48%

HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-...

Fosphenytoin disodium

T7066

Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

Dronedarone hydrochloride

T1073

Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.

Oxethazaine

T0044

Oxethazaine, a topical anesthetic, is used to prevent acid-induced esophageal pain.

Levobupivacaine hydrochloride

T6566

Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...