T7066 |
Fosphenytoin disodium
|
92134-98-0
|
99.91%
|
|
Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
|
T1073 |
Dronedarone hydrochloride
|
141625-93-6
|
99.91%
|
|
Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
|
T0044 |
Oxethazaine
|
126-27-2
|
99.92%
|
|
Oxethazaine, a topical anesthetic, is used to prevent acid-induced esophageal pain.
|
T6566 |
Levobupivacaine hydrochloride
|
27262-48-2
|
99.93%
|
|
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...
|
T0207 |
Ranolazine dihydrochloride
|
95635-56-6
|
99.93%
|
|
Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and...
|
T5S0890 |
Oleandrin
|
465-16-7
|
99.94%
|
|
1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional lev...
|
T4490 |
PF-01247324
|
875051-72-2
|
99.94%
|
|
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
|
T0267 |
Zonisamide
|
68291-97-4
|
99.94%
|
|
Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydra...
|
T0008 |
Phenytoin sodium
|
630-93-3
|
99.95%
|
|
Phenytoin sodium is an inactive stabilizer for voltage-gated sodium channel .
|
T0939 |
Phenytoin
|
57-41-0
|
99.95%
|
|
Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux fr...
|
T7811 |
Pilsicainide HCl
|
88069-49-2
|
99.96%
|
|
Pilsicainide HCl is a pure sodium channel blocker
|
TN1740 |
Homoeriodictyol
|
446-71-9
|
99.96%
|
|
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
|
T0924 |
Benzocaine
|
94-09-7
|
99.97%
|
|
Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
|
T0470 |
Nefopam hydrochloride
|
23327-57-3
|
99.97%
|
|
Nefopam Hydrochloride is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
|
T5319 |
Rimeporide
|
187870-78-6
|
99.98%
|
|
Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
|
T9461 |
AZ194
|
2241651-99-8
|
98%
|
|
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
|
T27794 |
λ-Cyhalothrin
|
91465-08-6
|
98%
|
|
lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. lambda-Cyhalothrin is used to control ...
|
T3021 |
Bulleyaconitine A
|
107668-79-1
|
98%
|
|
Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
|
TN5141 |
Thevetin B
|
27127-79-3
|
98%
|
|
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
|
T4699 |
5-(N,N-Hexamethylene)-amiloride
|
1428-95-1
|
85.48%
|
|
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-...
|