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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T12608 QX-314 chloride 5369-03-9 99.84%
QX-314 chloride
QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
T1386 Phenazopyridine hydrochloride 136-40-3 99.83%
Phenazopyridine hydrochloride
Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include na...
T0349 Riluzole 1744-22-5 99.81%
Riluzole
Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMY...
T39630 Zandatrigine 2154406-04-7 99.81%
Zandatrigine
Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy tre...
T16514 PF 04531083 1079400-07-9 99.81%
PF 04531083
PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.
T4S1876 3-Deoxyaconitine 3175-95-9 99.76%
3-Deoxyaconitine
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking...
T1409 Methocarbamol 532-03-6 99.75%
Methocarbamol
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment...
T19644 Benzonatate 104-31-4 99.75%
Benzonatate
Benzonatate is an antagonist of sodium channel protein.
T0249 N-Acetylprocainamide 32795-44-1 99.74%
N-Acetylprocainamide
N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic dr...
T1787 Levobupivacaine 27262-47-1 99.70%
Levobupivacaine
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. L...
T4008 Metergoline 17692-51-2 99.7%
Metergoline
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migrain...
T3364 Veratramine 60-70-8 99.7%
Veratramine
Veratramine (NSC-23880)(NSC-17821; NSC-23880) is a potent signal transduction inhibitor for treating tumors.
T2391 Camostat mesylate 59721-29-8 99.69%
Camostat mesylate
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
T0866 Propafenone 54063-53-5 99.69%
Propafenone
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
T6541 Ibutilide Fumarate 122647-32-9 99.68%
Ibutilide Fumarate
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, ...
T0024 Primidone 125-33-7 99.66%
Primidone
Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.
T0364 Dibucaine 85-79-0 99.64%
Dibucaine
Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.
T26086 Rilmakalim 132014-21-2 99.63%
Rilmakalim
Rilmakalim is a potassium channel opener. Rilmakalim shows antivasoconstrictor effect.
T8299 Dimethyl lithospermate B 875313-64-7 99.62%
Dimethyl lithospermate B
Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.
T0916 Butamben 94-25-7 99.61%
Butamben
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
QX-314 chloride
T12608
QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
Phenazopyridine hydrochloride
T1386
Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include na...
Riluzole
T0349
Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMY...
Zandatrigine
T39630
Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy tre...
PF 04531083
T16514
PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.
3-Deoxyaconitine
T4S1876
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking...
Methocarbamol
T1409
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment...
Benzonatate
T19644
Benzonatate is an antagonist of sodium channel protein.
N-Acetylprocainamide
T0249
N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic dr...
Levobupivacaine
T1787
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. L...
Metergoline
T4008
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migrain...
Veratramine
T3364
Veratramine (NSC-23880)(NSC-17821; NSC-23880) is a potent signal transduction inhibitor for treating tumors.
Camostat mesylate
T2391
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
Propafenone
T0866
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
Ibutilide Fumarate
T6541
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, ...
Primidone
T0024
Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.
Dibucaine
T0364
Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.
Rilmakalim
T26086
Rilmakalim is a potassium channel opener. Rilmakalim shows antivasoconstrictor effect.
Dimethyl lithospermate B
T8299
Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.
Butamben
T0916
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
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TargetMol