Reverse Transcriptase

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases are used by retroviruses to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, by eukaryotic cells to extend the telomeres at the ends of their linear chromosomes, and by some non-retroviruses such as the hepatitis B virus, a member of the Hepadnaviridae, which are dsDNA-RT viruses.

Cat. No.	Product name	CAS No.	Purity
T27154	Dexelvucitabine	134379-77-4	98%
T27154	Dexelvucitabine, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
T11189	Emtricitabine S-oxide	152128-77-3	98%
T11189	Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.Emtricitabine S-oxide (Emtricitabine sulfoxide) is a...
T0220	Foscarnet sodium	63585-09-1
T0220	Foscarnet sodium is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
T14489	Azvudine	1011529-10-4	100%
T14489	Azvudine is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strai...
T7447	Adefovir	106941-25-7	100%
T7447	Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection...
T0153	Oltipraz	64224-21-1	95.91%
T0153	Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as g...
T5981	2,2'-Anhydrouridine	3736-77-4	98%
T5981	2,2'-Cyclouridine is a research tool for antiviral and anticancer studies.
T1675	Adefovir dipivoxil	142340-99-6	98%
T1675	Adefovir Dipivoxil is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B vir...
T6519	Gramine	87-52-5	98.14%
T6519	Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for A...
T2901	Daidzin	552-66-9	98.28%
T2901	Daidzin is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T7282	Tenofovir alafenamide hemifumarate	1392275-56-7	98.37%
T7282	Tenofovir alafenamide fumarate (TAF) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV)
T19963	Alizarin Complexone	3952-78-1	98.78%
T19963	Alizarin Complexone is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent f...
T2330	Rilpivirine	500287-72-9	98.83%
T2330	Rilpivirine is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infec...
T9223	RO-0335	867365-76-2	98.9%
T9223	RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) a...
T12609	R-10015	2097938-51-5	98.97%
T12609	R-10015 is a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket(IC50 of 38 nM for human LIMK1),and a broad-spectrum a...
T1404	Stavudine	3056-17-5	99.15%
T1404	Stavudine, a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
T7111	Tenofovir Disoproxil	201341-05-1	99.17%
T7111	Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
T7700	Lersivirine	473921-12-9	99.26%
T7700	Lersivirine(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.
T3578	Pyridoxal phosphate	54-47-7	99.45%
T3578	Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic t...
T4326	AG 555	133550-34-2	99.51%
T4326	AG 555 is an EGFR tyrosine kinase inhibitor.