RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.

Cat. No.	Product name	CAS No.	Purity
T23077L	Novokinin acetate	T23077L	98%
T23077L	Novokinin acetate exhibited an affinity for the AT2 receptor with Ki of 7 nM, and its antihypertensive and vasorelaxing activities were blocked by PD123319, an A...
T35834L	(Sar¹)-Angiotensin II acetate	T35834L	98%
T35834L	(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with ...
T3064	VTP-27999	942142-51-0	98%
T3064	VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
T3178	BIBS 39	133085-33-3	98%
T3178	BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
T7743	ANGIOTENSIN IV TFA(12676-15-2(free base))	T7743	98%
T7743	ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.
T7577	Angiotensin III, human, mouse	13602-53-4	98%
T7577	Angiotensin III, human, mouse(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).
T7354	H-Val-Pro-Pro-OH	58872-39-2	98%
T7354	H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).
TP1528	Angiotensin I/II (1-5)	58442-64-1	98%
TP1528	Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.
T2400	Candesartan Cilexetil	145040-37-5	98%
T2400	Candesartan Cilexetil is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal ...
TP1016L	Aviptadil Acetate	1444827-29-5	98%
TP1016L	Avitadil acetate induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for resear...
T7616L	A 779 TFA(159432-28-7 free base)	T7616L	98%
T7616L	A 779(3TFA) is a potent antagonist of angiotensin-(1-7) receptor
T7510	Leucylarginylproline	133943-59-6	98%
T7510	Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).
T7339	Angiotensin (1-7)	51833-78-4	98%
T7339	Angiotensin 1-7, also known as Ang-(1-7), is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.6...
T0215	Losartan potassium	124750-99-8	98%
T0215	Losartan, an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
T6595	Moexipril hydrochloride	82586-52-5	98%
T6595	Moexipril HCl is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart fa...
T4431	Olodanrigan	1316755-16-4	98%
T4431	EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hypere...
TP2158	TRV-120027 TFA	TP2158	98%
TP2158	TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
T14337	Buloxibutid	477775-14-7	98%
T14337	Buloxibutid is a novel and selective small molecule angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and 10 μM for AT2 and AT1 receptors, respectivel...
T6219	Azilsartan Medoxomil	863031-21-4	98%
T6219	Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults wit...
T2322	Fimasartan	247257-48-3	98%
T2322	Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimas...