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RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T3753 Sinapinic Acid 530-59-6 99.92%
Sinapinic Acid
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p6...
T1615 Irbesartan 138402-11-6 99.92%
Irbesartan
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T1057 Azilsartan 147403-03-0 99.87%
Azilsartan
Azilsartan (TAK-536) is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiolog...
T4S0290 Araloside A 7518-22-1 99.87%
Araloside A
Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.
T0706 Lisinopril dihydrate 83915-83-7 99.87%
Lisinopril dihydrate
Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T7040 Angiotensin II human 4474-91-3 99.86%
Angiotensin II human
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimul...
TP1828 N-Acetyl-Ser-Asp-Lys-Pro 127103-11-1 99.85%
N-Acetyl-Ser-Asp-Lys-Pro
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-...
T1489 Fosinopril sodium 88889-14-9 99.84%
Fosinopril sodium
Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug tha...
T40220L TRV055 acetate T40220L 99.84%
TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.
T5S0106 Peimisine 19773-24-1 99.8%
Peimisine
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in orde...
T1484L Perindopril erbumine 107133-36-8 99.8%
Perindopril erbumine
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with...
T0215L Losartan 114798-26-4 99.79%
Losartan
Losartan (DuP-753) is an angiotensin II receptor antagonist.
T26594 Allisartan Isoproxil 947331-05-7 99.78%
Allisartan Isoproxil
Allisartan Isoproxil is a nonpeptide antagonist of angiotensin II receptor and can be used in studies about hypertension and heart diseases.
T6340 Enalaprilat Dihydrate 84680-54-6 99.78%
Enalaprilat Dihydrate
Enalaprilat Dihydrate (MK-422 Dihydrate) (IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.
T27357 FPL-62129 95445-79-7 99.76%
FPL-62129
FPL-62129 is a calcium channel antagonist and a novel angiotensin-converting enzyme inhibitor with vasodilator activity for the study of cardiovascular disease.
T66580 Azilsartan Methyl Ester 147403-52-9 99.74%
Azilsartan Methyl Ester
Azilsartan Methyl Ester is an angiotensin II receptor antagonist. Azilsartan Methyl Ester inhibits specific binding of [125I]AII (0.2 nM) to bovine adrenal corte...
TP1929L1 Saralasin acetate(34273-10-4 free base) 39698-78-7 99.74%
Saralasin acetate(34273-10-4 free base)
Saralasin acetate is a Non-selective angiotensin II antagonist.
T7668 VTP-27999 TFA 1013937-63-7 99.72%
VTP-27999 TFA
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
T1520 Aliskiren hemifumarate 173334-58-2 99.7%
Aliskiren hemifumarate
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T3178 BIBS 39 133085-33-3 99.69%
BIBS 39
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
Sinapinic Acid
T3753
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p6...
Irbesartan
T1615
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
Azilsartan
T1057
Azilsartan (TAK-536) is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiolog...
Araloside A
T4S0290
Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.
Lisinopril dihydrate
T0706
Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Angiotensin II human
T7040
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimul...
N-Acetyl-Ser-Asp-Lys-Pro
TP1828
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-...
Fosinopril sodium
T1489
Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug tha...
TRV055 acetate
T40220L
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.
Peimisine
T5S0106
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in orde...
Perindopril erbumine
T1484L
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with...
Losartan
T0215L
Losartan (DuP-753) is an angiotensin II receptor antagonist.
Allisartan Isoproxil
T26594
Allisartan Isoproxil is a nonpeptide antagonist of angiotensin II receptor and can be used in studies about hypertension and heart diseases.
Enalaprilat Dihydrate
T6340
Enalaprilat Dihydrate (MK-422 Dihydrate) (IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.
FPL-62129
T27357
FPL-62129 is a calcium channel antagonist and a novel angiotensin-converting enzyme inhibitor with vasodilator activity for the study of cardiovascular disease.
Azilsartan Methyl Ester
T66580
Azilsartan Methyl Ester is an angiotensin II receptor antagonist. Azilsartan Methyl Ester inhibits specific binding of [125I]AII (0.2 nM) to bovine adrenal corte...
Saralasin acetate(34273-10-4 free base)
TP1929L1
Saralasin acetate is a Non-selective angiotensin II antagonist.
VTP-27999 TFA
T7668
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
Aliskiren hemifumarate
T1520
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.
BIBS 39
T3178
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
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TargetMol