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RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T14123 ACT 178882 1007392-69-9 98%
ACT 178882
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).
T16544 Pivalopril 81045-50-3 98%
Pivalopril
Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.
T11809 L162441 154512-46-6 98%
L162441
L162441 is an antagonist of Angiotensin type 1 receptor.
T10323 Angiotensin II (3-8), human TFA T10323 98%
Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
T16573 Pratosartan 153804-05-8 98%
Pratosartan
Pratosartan is a selective antagonist of angiotensin II receptor.
T19187 Aliskiren D6 hemifumarate T19187 98%
Aliskiren D6 hemifumarate
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: ...
T16385 Omapatrilat 167305-00-2 98%
Omapatrilat
Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).
T6444 Cilazapril Monohydrate 92077-78-6 98%
Cilazapril Monohydrate
Cilazapril Monohydrate (Justor) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
T11808 L162389 169281-53-2 98%
L162389
L162389 is a potent angiotensin AT1 receptor antagonist with Ki of 28 nM.
T7616 A 779 159432-28-7 98%
A 779
A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.
T12704 Rentiapril 80830-42-8 98%
Rentiapril
Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.
TN4431 Leucosceptoside A 83529-62-8 98%
Leucosceptoside A
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidas...
TN1464 Camellianin A 109232-77-1 98%
Camellianin A
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 ...
T5824 Angiotensin II (3-8), human 12676-15-2 98%
Angiotensin II (3-8), human
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.
T6627 Phosphoramidon Disodium 164204-38-0 98%
Phosphoramidon Disodium
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.
T11642 Imidaprilate 89371-44-8 98%
Imidaprilate
Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the...
T7575 [Sar1, Ile8]-Angiotensin II 37827-06-8 98%
[Sar1, Ile8]-Angiotensin II
[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.
T2318 Sacubitril/Valsartan 936623-90-4 99.94%
Sacubitril/Valsartan
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failur...
T6542 Imidapril hydrochloride 89396-94-1 99.94%
Imidapril hydrochloride
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
T3753 Sinapinic Acid 530-59-6 99.92%
Sinapinic Acid
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p6...
ACT 178882
T14123
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).
Pivalopril
T16544
Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.
L162441
T11809
L162441 is an antagonist of Angiotensin type 1 receptor.
Angiotensin II (3-8), human TFA
T10323
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
Pratosartan
T16573
Pratosartan is a selective antagonist of angiotensin II receptor.
Aliskiren D6 hemifumarate
T19187
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: ...
Omapatrilat
T16385
Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).
Cilazapril Monohydrate
T6444
Cilazapril Monohydrate (Justor) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
L162389
T11808
L162389 is a potent angiotensin AT1 receptor antagonist with Ki of 28 nM.
A 779
T7616
A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.
Rentiapril
T12704
Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.
Leucosceptoside A
TN4431
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidas...
Camellianin A
TN1464
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 ...
Angiotensin II (3-8), human
T5824
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.
Phosphoramidon Disodium
T6627
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.
Imidaprilate
T11642
Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the...
[Sar1, Ile8]-Angiotensin II
T7575
[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.
Sacubitril/Valsartan
T2318
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failur...
Imidapril hydrochloride
T6542
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
Sinapinic Acid
T3753
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p6...
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TargetMol