T3880 |
Silydianin
|
29782-68-1
|
99.02%
|
|
Silydianin exerts inhibition of UGT in human liver. Silydianin exerts inhibition of OATP1B1, OATP1B3 (unknown origin) expressed in HEK293 cells. Silydianin exert...
|
T7084 |
2-Bromo-4'-hydroxyacetophenone
|
2491-38-5
|
99.07%
|
|
PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain...
|
T4852 |
Trimyristin
|
555-45-3
|
99.11%
|
|
Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ...
|
T9156 |
CDC25B-IN-2
|
134271-74-2
|
99.12%
|
|
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
|
T4308 |
F1063-0967
|
613225-56-2
|
99.15%
|
|
F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.
|
T14327 |
AS1949490
|
1203680-76-5
|
99.16%
|
|
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing in...
|
T20879 |
Tacrolimus monohydrate
|
109581-93-3
|
99.2%
|
|
Tacrolimus hydrate is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacro...
|
T8478 |
SC-43
|
1400989-25-4
|
99.26%
|
|
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and ...
|
TCS1372 |
Atraric acid
|
4707-47-5
|
99.27%
|
|
Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, that can be used for prophylaxis or treatment of pro...
|
T6521 |
GSK 2830371
|
1404456-53-6
|
99.3%
|
|
GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.
|
T2P2923 |
Stearic acid
|
57-11-4
|
99.31%
|
|
1. Stearic Acid can reduce metastatic tumor burden. 2. Stearic Acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. ...
|
T7704 |
KY-226
|
1621673-53-7
|
99.4%
|
|
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)
|
T4340 |
SPI-112
|
1051387-90-6
|
99.5%
|
|
SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competit...
|
T1210 |
Sodium etidronate
|
7414-83-7
|
99.5%
|
|
Etidronate Disodium is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, eti...
|
T3804 |
Neomangiferin
|
64809-67-2
|
99.51%
|
|
Neomangiferin has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant a...
|
TN2111 |
Prunin
|
529-55-5
|
99.52%
|
|
Prunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-re...
|
TQ0032 |
Rosiptor
|
782487-28-9
|
99.53%
|
|
Rosiptor (AQX-1125) is an orally-active and specific phosphatase SHIP1 activator with anti-inflammatory effects.
|
T4256 |
PTP1B-IN-2
|
1919853-46-5
|
99.58%
|
|
PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).
|
T3544 |
SHP099 hydrochloride
|
2200214-93-1
|
99.62%
|
|
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.
|
T13176 |
TNO155
|
1801765-04-7
|
99.63%
|
|
TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with pote...
|