PPAR

In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms.

Cat. No.	Product name	CAS No.	Purity
T1298	Clofibrate	637-07-0	99.87%
T1298	Clofibrate is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.
T8486	GW6471	880635-03-0	99.88%
T8486	GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMR...
T15453	GW7647	265129-71-3	99.89%
T15453	GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).
T8374	LJ570	2252488-69-8	99.89%
T8374	LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)
T4S1173	Agrimol B	55576-66-4	99.89%
T4S1173	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.
T1415	Gemfibrozil	25812-30-0	99.9%
T1415	Gemfibrozil interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an inc...
T2674	GSK0660	1014691-61-2	99.9%
T2674	GSK0660 is an antagonist and inverse agonist of PPARβ/δ.
TQ0107	Pemafibrate	848259-27-8	99.91%
TQ0107	Pemafibrate is a highly specific PPARα agonist (EC50: 1 nM).
T13803	N-Oleoyl glycine	2601-90-3	99.92%
T13803	N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte
T0061	Clofibric acid	882-09-7	99.93%
T0061	Clofibric acid is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
T2260	GW9662	22978-25-2	99.94%
T2260	GW9662 is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.
T6151	GW 501516	317318-70-0	99.94%
T6151	GW501516 is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.
T1402	Fenofibric acid	42017-89-0	99.94%
T1402	Fenofibric Acid is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.
T1674	Nateglinide	105816-04-4	99.94%
T1674	Nateglinide is an oral hypoglycemic agent and amino acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diab...
T1264	Ciprofibrate	52214-84-3	99.95%
T1264	Ciprofibrate is a fibrate derivative with antilipidemic activity.
T3941	Choline Fenofibrate	856676-23-8	99.95%
T3941	Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
TN1018	Angeloylgomisin H	66056-22-2	99.95%
TN1018	Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.
T2396	Ramatroban	116649-85-5	99.96%
T2396	Ramatroban (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of Asthma.
T1149	Fenofibrate	49562-28-9	99.97%
T1149	Fenofibrate is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic ...
T0448	(S)-(+)-Ibuprofen	51146-56-6	99.97%
T0448	Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).