TN1475 |
Caulophyllogenin
|
52936-64-8
|
98.56%
|
|
Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammat...
|
T3362 |
Eupatilin
|
22368-21-4
|
98.53%
|
|
Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.
|
T3710 |
XMD16-5
|
1345098-78-3
|
98.53%
|
|
XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted m...
|
T1941 |
GSK3787
|
188591-46-0
|
98.53%
|
|
GSK3787 is a specific and irreversible PPARδ inhibitor(pIC50= 6.6).
|
T2855 |
Icariin
|
489-32-7
|
98.49%
|
|
Icariin (Ieariline) is a flavonol glycoside, inhibiting PDE5 and PDE4 activities. Icariin also is a PPARα activator.
|
T8184 |
Fucosterol
|
17605-67-3
|
98.39%
|
|
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and ...
|
T4628 |
Seladelpar
|
851528-79-5
|
98.39%
|
|
Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.
|
T8486 |
GW6471
|
880635-03-0
|
98.38%
|
|
GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMR...
|
T2879 |
Fisetin
|
528-48-3
|
98.31%
|
|
Fisetin is a natural flavonol extracted from Rhus succedanea L that is structurally and functionally related to kaempferol, can modulate sirtuins,with antioxidan...
|
TQ0120 |
CDDO-Im
|
443104-02-7
|
98.3%
|
|
CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).
|
TN2290 |
Uvaol
|
545-46-0
|
98.27%
|
|
Uvaol is present in olives and virgin olive oil with anti-inflammatory, anti-proliferative, and vasorelaxant activities.
|
T19710 |
Ciglitazone
|
74772-77-3
|
98.23%
|
|
Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation o...
|
TQ0156 |
GW1929
|
196808-24-9
|
98.21%
|
|
GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).
|
TN1055 |
Licochalcone E
|
864232-34-8
|
98.09%
|
|
Licochalcone E is a potential LXRβ agonist.
|
T77612 |
WAY-620472
|
686769-90-4
|
98.07%
|
|
WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.
|
T68022L |
Sulotroban potassium
|
|
98.04%
|
|
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.
|
T3403 |
Glabridin
|
59870-68-7
|
98.01%
|
|
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS und...
|
T8780 |
AMG131
|
315224-26-1
|
98.01%
|
|
AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the...
|
T4S1545 |
Licarin B
|
51020-87-2
|
98%
|
|
1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.
|
T5701 |
OPHIOPOGONIN D
|
945619-74-9
|
98%
|
|
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
|