T6689 |
T0070907
|
313516-66-4
|
99.36%
|
|
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
|
T3954 |
Adelmidrol
|
1675-66-7
|
99.35%
|
|
Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.
|
T21587 |
Muraglitazar
|
331741-94-7
|
99.31%
|
|
Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitr...
|
T68022 |
Sulotroban
|
72131-33-0
|
99.29%
|
|
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
|
TN1525 |
Convallatoxin
|
508-75-8
|
99.27%
|
|
Convallatoxin is a natural product
|
T13289 |
EHP-101
|
1818428-24-8
|
99.22%
|
|
EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents di...
|
T63898 |
Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
|
849150-59-0
|
99.18%
|
|
Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo...
|
T6917 |
Oleuropein
|
32619-42-4
|
99.16%
|
|
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
|
T21955 |
GQ-16
|
870554-67-9
|
99.12%
|
|
GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.
|
T12268 |
NTP42
|
2055599-51-2
|
99.09%
|
|
NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
|
TN1693 |
Glabrone
|
60008-02-8
|
99.08%
|
|
Glabrone shows antiviral activity against influenza virus.
|
T21764 |
MCC-555
|
161600-01-7
|
99.07%
|
|
MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.
|
T15821 |
LY518674
|
425671-29-0
|
99.06%
|
|
LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis. LY518674 is an effective and selective PPARα agon...
|
TN1126 |
Sakuranetin
|
2957-21-3
|
99%
|
|
Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects
|
TN7060 |
Methyl oleanonate
|
1721-58-0
|
98.99%
|
|
3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.
|
T28501 |
Ragaglitazar
|
222834-30-2
|
98.95%
|
|
Ragaglitazar(NNC-61-0029) is a potent dual PPARα and PPARγ agonist that has shown potent lipid-lowering and insulin sensitizing effects in animal models.Ragaglit...
|
T7443 |
4'-Methoxychalcone
|
959-23-9
|
98.93%
|
|
4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.
|
TN1990 |
Norathyriol
|
3542-72-1
|
98.93%
|
|
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
|
T1238 |
Daidzein
|
486-66-8
|
98.84%
|
|
Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestr...
|
T15945 |
MA-0204
|
2095128-17-7
|
98.83%
|
|
MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human, mou...
|