TN3922 |
Effusanin E
|
76470-15-0
|
98%
|
|
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
|
TN1458 |
Buddlejasaponin IV
|
139523-30-1
|
98%
|
|
Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-ka...
|
T67844 |
RBN-3143
|
2360853-16-1
|
98%
|
|
RBN-3143 is a potent and inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM). RBN-3143 inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14...
|
TN4999 |
Serratenediol
|
2239-24-9
|
98%
|
|
Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects be...
|
TN3619 |
Cedrusin
|
75775-36-9
|
98%
|
|
Cedrusin shows a cytotoxic effect on A375 and HeLa cells.
|
T61189 |
E7016
|
902128-92-1
|
98%
|
|
E7016 is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.
|
T12366 |
PARP14 inhibitor H10
|
2084811-68-5
|
98%
|
|
PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
|
TN2106 |
Protodeltonin
|
94992-08-2
|
98%
|
|
Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhi...
|
TN4340 |
Ivangustin
|
14164-59-1
|
98%
|
|
Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines.
|
T5526 |
Glycoborinine
|
233279-39-5
|
98%
|
|
Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. Glycoborinine has photo-ac...
|
TN4028 |
Euchrestaflavanone B
|
87402-91-3
|
98%
|
|
Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanon...
|
TN1139 |
Dehydrocavidine
|
83218-34-2
|
98%
|
|
Dehydrocavidine has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well ...
|
T11992 |
Mefuparib hydrochloride
|
1449746-00-2
|
98%
|
|
Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo. Mefuparib hydrochloride (MPH) is an orally active, su...
|
TN1880 |
Lucidenic acid B
|
95311-95-8
|
98%
|
|
Lucidenic acid B shows antioxidative, and anti-invasive effects, it inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal tr...
|
TN2511 |
Britannilactone diacetate
|
1286694-67-4
|
98%
|
|
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airwa...
|
TN4932 |
Sageone
|
142546-15-4
|
98%
|
|
Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gast...
|
TN1728 |
Hellebrigenin
|
465-90-7
|
98%
|
|
Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. H...
|
TN1642 |
Ferruginol
|
514-62-5
|
98%
|
|
Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce ap...
|
T16979 |
Talazoparib tosylate
|
1373431-65-2
|
98%
|
|
Talazoparib tosylate is a novel and potent PARP1/2 (n IC50: 0.57 nM for PARP1).
|
TN4637 |
Neogrifolin
|
23665-96-5
|
98%
|
|
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ...
|