PARP

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes such as DNA repair, genomic stability, and programmed cell death.

Cat. No.	Product name	CAS No.	Purity
TN3922	Effusanin E	76470-15-0	98%
TN3922	Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
TN1458	Buddlejasaponin IV	139523-30-1	98%
TN1458	Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-ka...
T67844	RBN-3143	2360853-16-1	98%
T67844	RBN-3143 is a potent and inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM). RBN-3143 inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14...
TN4999	Serratenediol	2239-24-9	98%
TN4999	Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects be...
TN3619	Cedrusin	75775-36-9	98%
TN3619	Cedrusin shows a cytotoxic effect on A375 and HeLa cells.
T61189	E7016	902128-92-1	98%
T61189	E7016 is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.
T12366	PARP14 inhibitor H10	2084811-68-5	98%
T12366	PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
TN2106	Protodeltonin	94992-08-2	98%
TN2106	Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhi...
TN4340	Ivangustin	14164-59-1	98%
TN4340	Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines.
T5526	Glycoborinine	233279-39-5	98%
T5526	Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. Glycoborinine has photo-ac...
TN4028	Euchrestaflavanone B	87402-91-3	98%
TN4028	Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanon...
TN1139	Dehydrocavidine	83218-34-2	98%
TN1139	Dehydrocavidine has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well ...
T11992	Mefuparib hydrochloride	1449746-00-2	98%
T11992	Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo. Mefuparib hydrochloride (MPH) is an orally active, su...
TN1880	Lucidenic acid B	95311-95-8	98%
TN1880	Lucidenic acid B shows antioxidative, and anti-invasive effects, it inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal tr...
TN2511	Britannilactone diacetate	1286694-67-4	98%
TN2511	1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airwa...
TN4932	Sageone	142546-15-4	98%
TN4932	Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gast...
TN1728	Hellebrigenin	465-90-7	98%
TN1728	Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. H...
TN1642	Ferruginol	514-62-5	98%
TN1642	Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce ap...
T16979	Talazoparib tosylate	1373431-65-2	98%
T16979	Talazoparib tosylate is a novel and potent PARP1/2 (n IC50: 0.57 nM for PARP1).
TN4637	Neogrifolin	23665-96-5	98%
TN4637	Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ...