T6030 |
XL388
|
1251156-08-7
|
99.53%
|
|
XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.
|
T7056 |
Dronedarone
|
141626-36-0
|
99.55%
|
|
Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
|
T3610 |
Ranitidine
|
66357-35-5
|
99.56%
|
|
Ranitidine is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.
|
T1443 |
Memantine hydrochloride
|
41100-52-1
|
99.56%
|
|
Memantine hydrochloride is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
|
T22391 |
Omeprazole Sodium
|
95510-70-6
|
99.57%
|
|
Omeprazole Sodium, the sodium salt form of omeprazole, is a proton pump inhibitor and suppresses gastric acid secretion.
|
T6509 |
Galeterone
|
851983-85-2
|
99.57%
|
|
Galeterone is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibi...
|
T3698 |
Alpha-Asarone
|
2883-98-9
|
99.59%
|
|
Alpha-Asarone is a psychoactive compound with antidepressant-like activity in mice.
|
T3401 |
Ginsenoside F1
|
53963-43-2
|
99.6%
|
|
Ginsenoside F1 is an enzymatically modified derivative of ginsenoside Rg1, showing competitive inhibition of the activity of CYP3A4 and a weaker inhibition of th...
|
T21425 |
Mephenytoin
|
50-12-4
|
99.61%
|
|
Mephenytoin (racemic) is a hydantoin, used as an anticonvulsant.
|
T0679 |
Ketoconazole
|
65277-42-1
|
99.62%
|
|
Ketoconazole, a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
|
T6246 |
Cobicistat
|
1004316-88-4
|
99.62%
|
|
Cobicistat is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which...
|
TQ0296L |
N-Nornuciferine hydrochloride(4846-19-9 free base)
|
TQ0296L
|
99.63%
|
|
N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).
|
T6S0630 |
Hypaconitine
|
6900-87-4
|
99.63%
|
|
Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism.
|
T2770 |
Gentiopicroside
|
20831-76-9
|
99.64%
|
|
Gentiopicroside, a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22...
|
T3811 |
Ginsenoside C-K
|
39262-14-1
|
99.65%
|
|
Ginsenoside C-K is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.
|
T2175 |
Apigenin
|
520-36-5
|
99.66%
|
|
Chamomile is an aromatic oil extracted from the flowers or leaves of the daisy-like plants. Extracts, oils and teas made from chamomile are used for its soothing...
|
TN1023 |
Miltirone
|
27210-57-7
|
99.66%
|
|
Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.
|
T4567 |
Sulfaphenazole
|
526-08-9
|
99.67%
|
|
Sulfaphenazole is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18...
|
T0100 |
Atazanavir sulfate
|
229975-97-7
|
99.67%
|
|
Atazanavir sulfate is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS...
|
T5715 |
(E)-Flavokawain A
|
37951-13-6
|
99.7%
|
|
Flavokavin A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent ap...
|