T12171 |
Nampt-IN-5
|
2380013-17-0
|
99.3%
|
|
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
|
T1491 |
Atovaquone
|
95233-18-4
|
99.28%
|
|
Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
|
T6260 |
AMG-208
|
1002304-34-8
|
99.27%
|
|
AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
|
TP1313L |
Cecropin B acetate
|
|
99.27%
|
|
Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA se...
|
T3669 |
Curcumenol
|
19431-84-6
|
99.26%
|
|
Curcumenol ((+)-Curcumenol), one of the major components of Zedoary turmeric oil, is an antibiotic drug which has anti-Y, anti-inflammation activity. Curcumenol ...
|
T2840 |
Phloracetophenone
|
480-66-0
|
99.26%
|
|
Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of...
|
T77627 |
Opevesostat
|
2231294-96-3
|
99.25%
|
|
Opevesostat (ODM-208) is an inhibitor of lyase (CYP11A1) (the enzyme cleavage cholesterol side chain).
|
TN1011 |
Rhodionin
|
85571-15-9
|
99.24%
|
|
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administer...
|
T3417 |
Amentoflavone
|
1617-53-4
|
99.22%
|
|
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for ...
|
T11680 |
Isoasatone A
|
67451-73-4
|
99.21%
|
|
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity.
|
T10923 |
CYP17-IN-1
|
2093317-51-0
|
99.17%
|
|
CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
|
T2761 |
Naringin dihydrochalcone
|
18916-17-1
|
99.16%
|
|
Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.
|
T2878 |
Ginsenoside Rd
|
52705-93-8
|
99.13%
|
|
Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.
|
T9043 |
AS1810722
|
909561-15-5
|
99.13%
|
|
AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhi...
|
T0865 |
Ranitidine Hydrochloride
|
66357-59-3
|
99.13%
|
|
Ranitidine Hydrochloride (AH19065) is a member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversibl...
|
T0293 |
Metyrapone
|
54-36-4
|
99.12%
|
|
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the ...
|
T3610 |
Ranitidine
|
66357-35-5
|
99.1%
|
|
Ranitidine (HSDB 3925) is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestina...
|
T35716 |
N-desmethyl Olanzapine
|
161696-76-0
|
99.1%
|
|
N-desmethyl Olanzapine is a metabolite of the atypical antipsychotic compound Olanzapinec, which is formed through the oxidative metabolism of olanzapine by the ...
|
T16412 |
Oteseconazole
|
1340593-59-0
|
99.07%
|
|
Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Ca...
|
T37825 |
CAY10434
|
769917-29-5
|
99.07%
|
|
CAY10434 is an active inhibitor of CYP4A hydroxylase with an IC50 value of 8.8 nM in human kidney microsomal test. The maximum contractile value (Emax) of CAY 10...
|