T16739 |
RG-12525
|
120128-20-3
|
98%
|
|
RG-12525 is a PPAR-gamma agonist (IC50: appr 60 nM) and a potent inhibitor of CYP3A4 (Ki: 0.5 µM). RG-12525 is a specific and competitive antagonist of the pepti...
|
TQ0276 |
Methysticin
|
20697-20-5
|
98%
|
|
Methysticin, a major kavalactone extracted from kava, can induce CYP1A1.
|
T10535 |
BI 653048
|
1198784-72-3
|
98%
|
|
BI 653048 is a selective and orally active agonist of nonsteroidal glucocorticoid (IC50: 55 nM). BI 653048 is also an HCV NS3 protease inhibitor.
|
T14678 |
BMS-819881
|
1197420-05-5
|
98%
|
|
BMS-819881 is a melaninconcentrating hormone receptor 1 (MCHR1) antagonist, which binds rat MCHR1 with a Ki of 7 nM and it also is selective and potent for CYP3A...
|
TN3147 |
6',7'-Dihydroxybergamottin
|
264234-05-1
|
98%
|
|
6',7'-Dihydroxybergamottin(DHB), a well-known inhibitor of CYP3A4, the inhibition of CYP3A4 activity by DHB includes the inhibition of POR activity, DHB can inhi...
|
TN4424 |
Lecanoric acid
|
480-56-8
|
98%
|
|
Lecanoric acid shows antioxidant activity with an IC50 value of 79-95 ug/ml, it at 100 ug/ml conc. shows high growth stimulating activity in terms of increased d...
|
TN1378 |
α-Viniferin
|
62218-13-7
|
98%
|
|
α-Viniferin belongs to a class of organic compounds, also known as 2-arylbenzofuran flavonoids, that are inhibitors of prostaglandin H2 synthetase. α-Viniferin h...
|
TN4277 |
Isocupressic acid
|
1909-91-7
|
98%
|
|
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu...
|
T11066 |
DMU2139
|
1821143-80-9
|
98%
|
|
DMU2139 is a potent and specific CYP1B1 inhibitor with IC50s of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively.
|
TN3875 |
Dipterocarpol
|
471-69-2
|
98%
|
|
Dipterocarpol is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng. Dipterocarpol A shows moderate acetylcholinesterase inhibitory a...
|
TN3294 |
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate
|
67667-71-4
|
98%
|
|
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
|
T10891 |
CRTH2-IN-1
|
926661-54-3
|
98%
|
|
CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.
|
T37332 |
(±)-N-3-Benzylnirvanol
|
93879-40-4
|
98%
|
|
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll. (+) -n-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll are sele...
|
TN3627 |
Chalepensin
|
13164-03-9
|
98%
|
|
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential d...
|
TN4435 |
Licopyranocoumarin
|
117038-80-9
|
98%
|
|
Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane...
|
TN1748 |
Humantenirine
|
82375-30-2
|
98%
|
|
Standard reference
|
TN2144 |
Resveratroloside
|
38963-95-0
|
98%
|
|
Resveratroloside has cardioprotective effect, it exhibits α±-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4.
|
TN3574 |
Canadine
|
5096-57-1
|
98%
|
|
Canadine has antioxidant activity with low-toxic effect.
|
TMA0164 |
15-Hydroxydehydroabietic acid
|
54113-95-0
|
98%
|
|
15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities.
|
TN3379 |
Allocryptopine
|
24240-04-8
|
98%
|
|
Allocryptopine has certain effects on anti-injury for hepatocyte, ameliorating liver function, and prohibiting hepatic fibrosis; it increases mRNA levels of cyto...
|