T12078 |
ML334
|
1432500-66-7
|
98.06%
|
|
ML334 (LH601A) is a transmembrane and potent NRF2 activator that inhibits Keap1-NRF2 protein interactions to ameliorate myocardial infarction-induced cardiac fib...
|
T40063 |
CBR-470-1
|
2416095-06-0
|
98.03%
|
|
CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalen...
|
T1027 |
Luteolin
|
491-70-3
|
98%
|
|
Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities...
|
T5S1805 |
5,7-Dihydroxychromone
|
31721-94-5
|
98%
|
|
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. ...
|
T5364 |
TBHQ
|
1948-33-0
|
98%
|
|
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.
|
T2915 |
Bardoxolone
|
218600-44-3
|
97.9%
|
|
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activa...
|
T8979 |
AEM1
|
1030123-90-0
|
97.87%
|
|
AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing...
|
TMA1570 |
Sappanone A
|
102067-84-5
|
97.48%
|
|
Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-in...
|
T3012 |
Mangiferin
|
4773-96-0
|
96.74%
|
|
Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.
|
T0492 |
Dimethyl fumarate
|
624-49-7
|
90.51%
|
|
Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
|
T0973L |
Pyridoxine hydrochloride
|
58-56-0
|
100%
|
|
Pyridoxine hydrochloride (Vitamin B6) is the 4-methanol form of vitaminB6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino ac...
|
T1368 |
Methyl 3,4-dihydroxybenzoate
|
2150-43-8
|
100%
|
|
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflamm...
|
TN2272 |
Tigloylgomisin H
|
66069-55-4
|
98%
|
|
Tigloylgomisin H represents a potential liver cancer prevention agent, it can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarci...
|
TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
TP2109L |
AT 14 acetate
|
|
98%
|
|
TAT 14 acetate, a 14-mer peptide, is an Nrf2 activator with anti-inflammatory properties. TAT 14 acetate increases Nrf2 protein levels due to targeting the Nrf2 ...
|
TN5171 |
Tricetin
|
520-31-0
|
98%
|
|
Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkins...
|
T1593 |
Ezetimibe
|
163222-33-1
|
98%
|
|
Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.
|
T8281 |
(R)-Sulforaphane
|
142825-10-3
|
98%
|
|
(R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway.
|
T2A2486 |
3',4',5',5,7-Pentamethoxyflavone
|
53350-26-8
|
98%
|
|
3',4',5',5,7-Pentamethoxyflavone is a naturally occurring brassinosteroid compound from the Rutaceae family that exhibits resistance to cancer cells by inhibitin...
|
T39719 |
Nrf2 activator-1
|
2230697-41-1
|
98%
|
|
Nrf2 activator-1 is a potent activator of NF-E2-related factor 2 (Nrf2).Nrf2 activator-1 can be used to study COPD and other respiratory diseases including asthm...
|