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Neuropeptide Y Receptor

Neuropeptide Y receptors are a family of receptors belonging to class A G-protein coupled receptors and they are activated by the closely related peptide hormones neuropeptide Y, peptide YY and pancreatic polypeptide. These receptors are involved in the control of a diverse set of behavioral processes including appetite, circadian rhythm, and anxiety.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T22994 ML 154 1345964-89-7 99.44%
ML 154
neuropeptide S receptor (NPSR) antagonist
T16738L RF9 acetate 99.35%
RF9 acetate
RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.
TP1991L M 1145 acetate 99.1%
M 1145 acetate
M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affi...
T23087 NPY 5RA972 439861-56-0 99.02%
NPY 5RA972
neuropeptide Y Y5 receptor antagonist
T10539 BIBO3304 TFA 191868-14-1 98.87%
BIBO3304 TFA
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 recept...
T5455 HT-2157 303149-14-6 98.55%
HT-2157
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
TP1884L1 Neuropeptide SF(mouse,rat) acetate TP1884L1 98.37%
Neuropeptide SF(mouse,rat) acetate
Neuropeptide SF(mouse,rat) acetate (Neuropeptide SF(mouse,rat) acetate (230960-31-3 free base)) is a potent neuropeptide FF receptor agonist, Ki for NPFF1 and NP...
TP1074L Neuropeptide FF acetate(99566-27-5 free base) TP1074L 98.03%
Neuropeptide FF acetate(99566-27-5 free base)
Neuropeptide FF acetate(99566-27-5 free base) (NPFF acetate) is an octapeptide belonging to the RF amide family. NPFF interacts with G-protein-coupled receptors ...
T23094 NTNCB hydrochloride 191931-56-3 97.92%
NTNCB hydrochloride
NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.
T15368L Galantide acetate 97.8%
Galantide acetate
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two ...
TP1936L1 RFRP3(human) acetate(311309-27-0 free base) TP1936L1 97.09%
RFRP3(human) acetate(311309-27-0 free base)
RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a ...
T8963 CYM2503 1308833-36-4 97.04%
CYM2503
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthos...
T21611L BWX 46 Acetate T21611L 96.86%
BWX 46 Acetate
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM.
TP1937L1 RFRP-1 (human) acetate(311309-25-8 free base) TP1937L1 96.84%
RFRP-1 (human) acetate(311309-25-8 free base)
RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile ...
TP1930L1 Spexin acetate(1370290-58-6 free base) TP1930L1 95.43%
Spexin acetate(1370290-58-6 free base)
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galani...
T21646L AR-M 1896 Acetate T21646L 95.32%
AR-M 1896 Acetate
AR-M 1896 Acetate is the selective agonist of GalR2.
T24121 GW438014A 469861-49-2 100%
GW438014A
GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.
T10056 Neurokinin antagonist 1 214487-45-3 100%
Neurokinin antagonist 1
Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.
T1997 JNJ-31020028 1094873-14-9
JNJ-31020028
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold ...
T71749 SF-22 824981-55-7 98%
SF-22
SF-22 is a neuropeptide Y receptor (Y2R) antagonist that crosses the blood-brain barrier and has potential anti-inflammatory activity for the study of diseases a...
ML 154
T22994
neuropeptide S receptor (NPSR) antagonist
RF9 acetate
T16738L
RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.
M 1145 acetate
TP1991L
M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affi...
NPY 5RA972
T23087
neuropeptide Y Y5 receptor antagonist
BIBO3304 TFA
T10539
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 recept...
HT-2157
T5455
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
Neuropeptide SF(mouse,rat) acetate
TP1884L1
Neuropeptide SF(mouse,rat) acetate (Neuropeptide SF(mouse,rat) acetate (230960-31-3 free base)) is a potent neuropeptide FF receptor agonist, Ki for NPFF1 and NP...
Neuropeptide FF acetate(99566-27-5 free base)
TP1074L
Neuropeptide FF acetate(99566-27-5 free base) (NPFF acetate) is an octapeptide belonging to the RF amide family. NPFF interacts with G-protein-coupled receptors ...
NTNCB hydrochloride
T23094
NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.
Galantide acetate
T15368L
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two ...
RFRP3(human) acetate(311309-27-0 free base)
TP1936L1
RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a ...
CYM2503
T8963
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthos...
BWX 46 Acetate
T21611L
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM.
RFRP-1 (human) acetate(311309-25-8 free base)
TP1937L1
RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile ...
Spexin acetate(1370290-58-6 free base)
TP1930L1
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galani...
AR-M 1896 Acetate
T21646L
AR-M 1896 Acetate is the selective agonist of GalR2.
GW438014A
T24121
GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.
Neurokinin antagonist 1
T10056
Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.
JNJ-31020028
T1997
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold ...
SF-22
T71749
SF-22 is a neuropeptide Y receptor (Y2R) antagonist that crosses the blood-brain barrier and has potential anti-inflammatory activity for the study of diseases a...
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TargetMol