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Neurokinin receptor

The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P, although it has some affinity for other tachykinins.
Cat. No. Product name CAS No. Purity Chemical Structure
TQ0087 NKP608 177707-12-9 98%
NKP608 is a selective and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50: 2.6 nM) and in vivo.
TP1177 Eledoisin 69-25-0 98%
Eledoisin is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.
T16406 Orvepitant maleate 579475-24-4 98%
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant...
T7559 Neurokinin A(4-10) 97559-35-8 98%
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .
T7396 Substance P(1-7) 68060-49-1 98%
Substance P 1-7 is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptiv...
T7631 Eledoisin Related Peptide 2990-43-4 98%
Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand.
T10892 CS-003 Free base 191672-52-3 98%
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 ...
T19518 Physalaemin 2507-24-6 98%
Physalaemin is a non-mammalian tachykinin.
T13329 Vofopitant 168266-90-8 98%
Vofopitant is a potent antagonist of the tachykinin NK1 receptor (pKis: 10.6, 9.5, and 9.8 for the human, rat, and ferret NK1 receptor, respectively).
T35344 Maropitant citrate 359875-09-5 98%
T13329L Vofopitant dihydrochloride 168266-51-1 98%
Vofopitant dihydrochloride is a selective and orally available antagonist of tachykinin neurokinin 1(NK1) receptor (pKi: 9.5 and 10.6 in rat and human membranes ...
T10688 Casopitant mesylate 414910-30-8 98%
Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of anti...
TP1851L Scyliorhinin II acetate TP1851L 98%
Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.
T38144 Elinzanetant 929046-33-3 98%
Elinzanetant is a neurokinin receptors antagonist used for the research of Schizophrenia[1]. [1]. Alvaro, Giuseppe; Andreotti, Daniele; Belvedere, Sandro; Di Fab...
T24697L R 396 acetate 98%
R 396 acetate is an NK-2 Tachykinin Receptor Antagonist.
T19518L Physalaemin acetate 98%
Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor.
T17156 Tradipitant 622370-35-8 98%
Tradipitant is an antagonist of neurokinin-1.
T24446L MEN 10207 acetate 98%
MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor.
T20413L Spantide acetate T20413L 98%
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
T23316 SB 218795 174635-53-1 98%
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1.
NKP608
TQ0087
NKP608 is a selective and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50: 2.6 nM) and in vivo.
Eledoisin
TP1177
Eledoisin is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.
Orvepitant maleate
T16406
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant...
Neurokinin A(4-10)
T7559
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .
Substance P(1-7)
T7396
Substance P 1-7 is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptiv...
Eledoisin Related Peptide
T7631
Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand.
CS-003 Free base
T10892
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 ...
Physalaemin
T19518
Physalaemin is a non-mammalian tachykinin.
Vofopitant
T13329
Vofopitant is a potent antagonist of the tachykinin NK1 receptor (pKis: 10.6, 9.5, and 9.8 for the human, rat, and ferret NK1 receptor, respectively).
Maropitant citrate
T35344
Vofopitant dihydrochloride
T13329L
Vofopitant dihydrochloride is a selective and orally available antagonist of tachykinin neurokinin 1(NK1) receptor (pKi: 9.5 and 10.6 in rat and human membranes ...
Casopitant mesylate
T10688
Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of anti...
Scyliorhinin II acetate
TP1851L
Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.
Elinzanetant
T38144
Elinzanetant is a neurokinin receptors antagonist used for the research of Schizophrenia[1]. [1]. Alvaro, Giuseppe; Andreotti, Daniele; Belvedere, Sandro; Di Fab...
R 396 acetate
T24697L
R 396 acetate is an NK-2 Tachykinin Receptor Antagonist.
Physalaemin acetate
T19518L
Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor.
Tradipitant
T17156
Tradipitant is an antagonist of neurokinin-1.
MEN 10207 acetate
T24446L
MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor.
Spantide acetate
T20413L
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
SB 218795
T23316
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1.
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