T9222L |
Emlenoflast sodium
|
2380032-29-9
|
98%
|
|
Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, a...
|
T9222 |
Emlenoflast
|
1995067-59-8
|
98%
|
|
Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.
|
T6591 |
Nodinitib-1
|
799264-47-4
|
99.98%
|
|
Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
|
T9572 |
BMS986299
|
2242952-69-6
|
99.93%
|
|
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
|
T61786 |
Selnoflast
|
2260969-36-4
|
99.82%
|
|
Selnoflast (example 6) is a NLRP3 inhibitor[1].
|
T4217 |
INF39
|
866028-26-4
|
99.67%
|
|
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
|
T61392 |
NLRP3-IN-10
|
2641826-39-1
|
99.63%
|
|
NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation...
|
TQ0165 |
Arglabin
|
84692-91-1
|
99.62%
|
|
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
|
TN1273 |
7,4'-Dihydroxyflavone
|
2196-14-7
|
99.6%
|
|
7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-...
|
T3587 |
NOD-IN-1
|
132819-92-2
|
99.43%
|
|
NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
|
T79906 |
ADS032
|
2757333-37-0
|
99.33%
|
|
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β pr...
|
T38361 |
GSK717
|
1595278-21-9
|
99.01%
|
|
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
|
T0122 |
Bergenin
|
477-90-7
|
99.01%
|
|
Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
|
T3230 |
NLRP3-IN-2
|
16673-34-0
|
98.98%
|
|
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation o...
|
T27841 |
Lobeglitazone Sulfate
|
763108-62-9
|
98.69%
|
|
Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and h...
|
T25548 |
JC124
|
1638611-48-9
|
98.54%
|
|
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
|
TN2063 |
Physalin B
|
23133-56-4
|
98.40%
|
|
Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammat...
|
T3092 |
Nigericin sodium salt
|
28643-80-3
|
98.2%
|
|
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which...
|
T6887 |
MCC950 sodium
|
256373-96-3
|
98.16%
|
|
MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs). MCC950 sodiu...
|
T2845 |
Imperatorin
|
482-44-0
|
98.07%
|
|
Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and m...
|