NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.

Cat. No.	Product name	CAS No.	Purity
T61392	NLRP3-IN-10	2641826-39-1	98%
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
T25548	JC124	1638611-48-9	98%
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
T9222	Emlenoflast	1995067-59-8	98%
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
T3701	MCC950	210826-40-7	98%
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
T28178	NLRP3-IN-9	88039-46-7	98%
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
T13375	YQ128	2454246-18-3
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T15052	Dapansutrile	54863-37-5
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T4164	CY-09	1073612-91-5	100%
CY-09 is an NLRP3 inhibitor.
T7597	6-Biopterin	22150-76-1	95.95%
6-Biopterin is a natural product,is a NO synthase cofactor.
T7682	Asymmetric dimethylarginine	30315-93-6	98%
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T5838	L-Canavanine sulfate	2219-31-0	98%
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
T2845	Imperatorin	482-44-0	98.07%
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T3230	NLRP3-IN-2	16673-34-0	98.98%
It is a NLRP3 Inflammasome Inhibitor I.
T38361	GSK717	1595278-21-9	99.01%
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T6887	MCC950 sodium	256373-96-3	99.12%
MCC950 sodium salt (IC50 of 7.5 uM in BMDMs) is an effective, selective NLRP3 inhibitor.
T6S1367	Procyanidin B2	29106-49-8	99.21%
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
T0122	Bergenin	477-90-7	99.43%
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
TN1273	7,4'-Dihydroxyflavone	2196-14-7	99.6%
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
TQ0165	Arglabin	84692-91-1	99.62%
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
T3587	NOD-IN-1	132819-92-2	99.67%
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T61392

NLRP3-IN-10

2641826-39-1

98%

NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...

T25548

JC124

1638611-48-9

98%

JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.

T9222

Emlenoflast

1995067-59-8

98%

Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.

T3701

MCC950

210826-40-7

98%

CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...

T28178

NLRP3-IN-9

88039-46-7

98%

NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...

T13375

YQ128

2454246-18-3

YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.

T15052

Dapansutrile

54863-37-5

Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.

T4164

CY-09

1073612-91-5

100%

CY-09 is an NLRP3 inhibitor.

T7597

6-Biopterin

22150-76-1

95.95%

6-Biopterin is a natural product,is a NO synthase cofactor.

T7682

Asymmetric dimethylarginine

30315-93-6

98%

Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)

T5838

L-Canavanine sulfate

2219-31-0

98%

L-Canavanine sulfate is a selective inducible NO synthase inhibitor.

T2845

Imperatorin

482-44-0

98.07%

Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.

T3230

NLRP3-IN-2

16673-34-0

98.98%

It is a NLRP3 Inflammasome Inhibitor I.

T38361

GSK717

1595278-21-9

99.01%

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...

T6887

MCC950 sodium

256373-96-3

99.12%

MCC950 sodium salt (IC50 of 7.5 uM in BMDMs) is an effective, selective NLRP3 inhibitor.

T6S1367

Procyanidin B2

29106-49-8

99.21%

Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...

T0122

Bergenin

477-90-7

99.43%