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NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.
Cat. No. Product name CAS No. Purity Chemical Structure
T61392 NLRP3-IN-10 2641826-39-1 98%
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
T25548 JC124 1638611-48-9 98%
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
T9222 Emlenoflast 1995067-59-8 98%
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
T3701 MCC950 210826-40-7 98%
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
T28178 NLRP3-IN-9 88039-46-7 98%
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
T13375 YQ128 2454246-18-3
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T15052 Dapansutrile 54863-37-5
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T4164 CY-09 1073612-91-5 100%
CY-09 is an NLRP3 inhibitor.
T7597 6-Biopterin 22150-76-1 95.95%
6-Biopterin is a natural product,is a NO synthase cofactor.
T7682 Asymmetric dimethylarginine 30315-93-6 98%
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T5838 L-Canavanine sulfate 2219-31-0 98%
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
T2845 Imperatorin 482-44-0 98.07%
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T3230 NLRP3-IN-2 16673-34-0 98.98%
It is a NLRP3 Inflammasome Inhibitor I.
T38361 GSK717 1595278-21-9 99.01%
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T6887 MCC950 sodium 256373-96-3 99.12%
MCC950 sodium salt (IC50 of 7.5 uM in BMDMs) is an effective, selective NLRP3 inhibitor.
T6S1367 Procyanidin B2 29106-49-8 99.21%
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
T0122 Bergenin 477-90-7 99.43%
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
TN1273 7,4'-Dihydroxyflavone 2196-14-7 99.6%
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
TQ0165 Arglabin 84692-91-1 99.62%
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
T3587 NOD-IN-1 132819-92-2 99.67%
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
NLRP3-IN-10
T61392
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
JC124
T25548
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
Emlenoflast
T9222
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
MCC950
T3701
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
NLRP3-IN-9
T28178
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
YQ128
T13375
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
Dapansutrile
T15052
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
CY-09
T4164
CY-09 is an NLRP3 inhibitor.
6-Biopterin
T7597
6-Biopterin is a natural product,is a NO synthase cofactor.
Asymmetric dimethylarginine
T7682
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
L-Canavanine sulfate
T5838
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
Imperatorin
T2845
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
NLRP3-IN-2
T3230
It is a NLRP3 Inflammasome Inhibitor I.
GSK717
T38361
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
MCC950 sodium
T6887
MCC950 sodium salt (IC50 of 7.5 uM in BMDMs) is an effective, selective NLRP3 inhibitor.
Procyanidin B2
T6S1367
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
Bergenin
T0122
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
7,4'-Dihydroxyflavone
TN1273
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
Arglabin
TQ0165
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
NOD-IN-1
T3587
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
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