T61392 |
NLRP3-IN-10
|
2641826-39-1
|
98%
|
|
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
|
T25548 |
JC124
|
1638611-48-9
|
98%
|
|
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
|
T9222 |
Emlenoflast
|
1995067-59-8
|
98%
|
|
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
|
T3701 |
MCC950
|
210826-40-7
|
98%
|
|
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
|
T28178 |
NLRP3-IN-9
|
88039-46-7
|
98%
|
|
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
|
T13375 |
YQ128
|
2454246-18-3
|
|
|
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
|
T15052 |
Dapansutrile
|
54863-37-5
|
|
|
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
|
T4164 |
CY-09
|
1073612-91-5
|
100%
|
|
CY-09 is an NLRP3 inhibitor.
|
T7597 |
6-Biopterin
|
22150-76-1
|
95.95%
|
|
6-Biopterin is a natural product,is a NO synthase cofactor.
|
T7682 |
Asymmetric dimethylarginine
|
30315-93-6
|
98%
|
|
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
|
T5838 |
L-Canavanine sulfate
|
2219-31-0
|
98%
|
|
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
|
T2845 |
Imperatorin
|
482-44-0
|
98.07%
|
|
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
|
T3230 |
NLRP3-IN-2
|
16673-34-0
|
98.98%
|
|
It is a NLRP3 Inflammasome Inhibitor I.
|
T38361 |
GSK717
|
1595278-21-9
|
99.01%
|
|
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
|
T6887 |
MCC950 sodium
|
256373-96-3
|
99.12%
|
|
MCC950 sodium salt (IC50 of 7.5 uM in BMDMs) is an effective, selective NLRP3 inhibitor.
|
T6S1367 |
Procyanidin B2
|
29106-49-8
|
99.21%
|
|
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
|
T0122 |
Bergenin
|
477-90-7
|
99.43%
|
|
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
|
TN1273 |
7,4'-Dihydroxyflavone
|
2196-14-7
|
99.6%
|
|
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
|
TQ0165 |
Arglabin
|
84692-91-1
|
99.62%
|
|
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
|
T3587 |
NOD-IN-1
|
132819-92-2
|
99.67%
|
|
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
|