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NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T9222 Emlenoflast 1995067-59-8 98.19%
Emlenoflast
Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.
T16159 Muramyl dipeptide 53678-77-6 100%
Muramyl dipeptide
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramy...
T9222L Emlenoflast sodium 2380032-29-9 98%
Emlenoflast sodium
Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, a...
T6591 Nodinitib-1 799264-47-4 99.98%
Nodinitib-1
Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
T9572 BMS986299 2242952-69-6 99.93%
BMS986299
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
T61786 Selnoflast 2260969-36-4 99.82%
Selnoflast
Selnoflast (example 6) is a NLRP3 inhibitor[1].
T4217 INF39 866028-26-4 99.67%
INF39
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
T13375 YQ128 2454246-18-3 99.67%
YQ128
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T61392 NLRP3-IN-10 2641826-39-1 99.63%
NLRP3-IN-10
NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation...
TQ0165 Arglabin 84692-91-1 99.62%
Arglabin
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
TN1273 7,4'-Dihydroxyflavone 2196-14-7 99.6%
7,4'-Dihydroxyflavone
7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-...
T3092 Nigericin sodium salt 28643-80-3 99.52%
Nigericin sodium salt
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which...
T3587 NOD-IN-1 132819-92-2 99.43%
NOD-IN-1
NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
T79906 ADS032 2757333-37-0 99.33%
ADS032
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β pr...
T38361 GSK717 1595278-21-9 99.01%
GSK717
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T0122 Bergenin 477-90-7 99.01%
Bergenin
Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
T3230 NLRP3-IN-2 16673-34-0 98.98%
NLRP3-IN-2
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation o...
T27841 Lobeglitazone Sulfate 763108-62-9 98.69%
Lobeglitazone Sulfate
Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and h...
T25548 JC124 1638611-48-9 98.54%
JC124
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
TN2063 Physalin B 23133-56-4 98.40%
Physalin B
Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammat...
Emlenoflast
T9222
Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.
Muramyl dipeptide
T16159
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramy...
Emlenoflast sodium
T9222L
Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, a...
Nodinitib-1
T6591
Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
BMS986299
T9572
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
Selnoflast
T61786
Selnoflast (example 6) is a NLRP3 inhibitor[1].
INF39
T4217
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
YQ128
T13375
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
NLRP3-IN-10
T61392
NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation...
Arglabin
TQ0165
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
7,4'-Dihydroxyflavone
TN1273
7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-...
Nigericin sodium salt
T3092
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which...
NOD-IN-1
T3587
NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
ADS032
T79906
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β pr...
GSK717
T38361
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
Bergenin
T0122
Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
NLRP3-IN-2
T3230
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation o...
Lobeglitazone Sulfate
T27841
Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and h...
JC124
T25548
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
Physalin B
TN2063
Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammat...
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TargetMol