TN4652 |
Niazimicin
|
147821-49-6
|
98%
|
|
Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity in...
|
TN4064 |
Flavoglaucin
|
523-73-9
|
98%
|
|
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
TN4171 |
Grossamide
|
80510-06-1
|
98%
|
|
Grossamide possesses potential anti-inflammatory effects, it also has potential anti-neuroinflammatory effects against lipopolysaccharide (LPS)-induced inflammat...
|
T4366 |
Quinovic acid
|
465-74-7
|
98%
|
|
Quinovic acid shows some anti-tumour activities, quinovic acid glycosides have a potent inhibitory effect on the growth of human bladder cancer cell lines by ind...
|
TN2641 |
15-Methoxypinusolidic acid
|
769928-72-5
|
98%
|
|
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methox...
|
T61233 |
Penehyclidine hydrochloride
|
151937-76-7
|
98%
|
|
Penehyclidine hydrochloride is an M1 and M3 antagonist and activates NF-κB in lung tissue. Penehyclidine hydrochloride inhibits the release of inflammatory facto...
|
TN2177 |
Sanggenol L
|
329319-20-2
|
98%
|
|
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
|
TN1504 |
Citreorosein
|
481-73-2
|
98%
|
|
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both...
|
TN1806 |
Isotetrandrine
|
477-57-6
|
98%
|
|
Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of...
|
T10808 |
CHPG sodium salt
|
1303993-73-8
|
98%
|
|
CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways. CHPG sodium salt can be used in studies about traumatic brain...
|
TN2178 |
Sanggenone H
|
86450-80-8
|
98%
|
|
Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α² and inhibited the NF-κB nuclear translocation in LPS-stimulated m...
|
TN1832 |
Kanzonol C
|
151135-82-9
|
98%
|
|
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sho...
|
T11886 |
LTβR-IN-1
|
2189366-77-4
|
98%
|
|
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12...
|
TN1104 |
Cyanidin 3-sambubioside chloride
|
33012-73-6
|
98%
|
|
Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing with the substrate for the active s...
|
TN1484 |
Cheilanthifoline
|
483-44-3
|
98%
|
|
Cheilanthifoline has anti-osteoclastogenic property, it gives significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation o...
|
T15204 |
EHT 1610
|
1425945-60-3
|
98%
|
|
EHT 1610 is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, r...
|
TN4213 |
Hirsutenone
|
41137-87-5
|
98%
|
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
|
TN2095 |
Pomiferin
|
572-03-2
|
98%
|
|
Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has a...
|
TN1485 |
Chicanine
|
78919-28-5
|
98%
|
|
Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.
|