T79999 |
NF-κB-IN-13
|
117596-92-6
|
98%
|
|
NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1]....
|
T80062 |
Mitogen-activated protein kinase 1
|
137632-08-7
|
98%
|
|
Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases. Its catalytic action p...
|
T80208 |
Tripeptide-41
|
1093241-16-7
|
98%
|
|
Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation. It has been utilized as an ingredient in cosmetic formulation...
|
T82022 |
IVMT-Rx-3
|
|
98%
|
|
IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin. It effectively blocks the MDA-9...
|
T82049 |
IR-Crizotinib
|
2387927-74-2
|
98%
|
|
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial ...
|
T82665 |
CTP-NBD
|
1268513-27-4
|
98%
|
|
CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2].
|
T83052 |
Anti-inflammatory agent 60
|
|
98%
|
|
Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin ex...
|
TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
TN1806 |
Isotetrandrine
|
477-57-6
|
98%
|
|
Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of...
|
TN1485 |
Chicanine
|
78919-28-5
|
98%
|
|
Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.
|
TN2095 |
Pomiferin
|
572-03-2
|
98%
|
|
Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has a...
|
TMA1777 |
Hydrangenol 8-O-glucoside
|
67600-94-6
|
98%
|
|
Hydrangenol 8-O-glucoside may have anti-inflammary activity.
|
TN3410 |
Anatabine
|
581-49-7
|
98%
|
|
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheime...
|
TN4633 |
Neocryptotanshinone II
|
27468-20-8
|
98%
|
|
Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways.
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
|
T4366 |
Quinovic acid
|
465-74-7
|
98%
|
|
Quinovic acid shows some anti-tumour activities, quinovic acid glycosides have a potent inhibitory effect on the growth of human bladder cancer cell lines by ind...
|
TN1764 |
Incensole acetate
|
34701-53-6
|
98%
|
|
Incensole acetate is a novel anti-inflammatory compound that inhibits NF-κB activation.
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
TN2451 |
Isosalvianolic acid B
|
930573-88-9
|
98%
|
|
Isosalvianolic acid B is a natural from Salviae miltiorrhizae
|