T16290 |
NIK SMI1
|
1660114-31-7
|
98%
|
|
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).
|
T6S0840 |
Engeletin
|
572-31-6
|
98%
|
|
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engelet...
|
TD0099 |
Malachite green oxalate
|
2437-29-8
|
98%
|
|
Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.
|
T0307 |
Tyloxapol
|
25301-02-4
|
98%
|
|
Tyloxapol is a non-ionic liquid polymer used as a surfactant.
|
TN5153 |
Torilin
|
13018-10-5
|
98%
|
|
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic...
|
TN4046 |
Excisanin A
|
78536-37-5
|
98%
|
|
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
|
TN1094 |
Ginsenoside Rg6
|
147419-93-0
|
98%
|
|
Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an incr...
|
T27034 |
CL075
|
256922-53-9
|
98%
|
|
CL075 is a selective TLR8 agonist.CL075 has immunomodulatory activity by triggering the MyD88-dependent signaling pathway, activating NF-κB and IRF7 to elicit th...
|
T3816 |
Velutin
|
25739-41-7
|
98%
|
|
Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as ...
|
TN5019 |
Siegeskaurolic acid
|
52645-97-3
|
98%
|
|
Siegeskaurolic acid exhibits anti-inflammatory and antinociceptive effects, which due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via...
|
TN3144 |
6,4'-Dihydroxy-7-methoxyflavanone
|
189689-32-5
|
98%
|
|
6,4'-Dihydroxy-7-methoxyflavanone is a biologically active compound isolated from the heartwood of Dalbergia odorifera T. Chen (Leguminosae) with antioxidant, an...
|
TN1598 |
Dunnianol
|
139726-29-7
|
98%
|
|
Dunnianol shows anti-inflammatory activity and moderate antibacterial activity.
|
TN3119 |
5-Hydroxy-7,8-dimethoxyflavanone
|
113981-49-0
|
98%
|
|
5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.
|
T21577 |
Narasin (sodium salt)
|
58331-17-2
|
98%
|
|
Narasin induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by su...
|
TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
|
TN1694 |
Gliotoxin
|
67-99-2
|
98%
|
|
Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signalin...
|
TP1373L |
Ac2-26 acetate
|
|
98%
|
|
Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1). Ac2-26 acetate decreases AnxA1 protein expression and inhibits the activation of NF-κB and M...
|
T7980 |
Hesperidin methylchalcone
|
24292-52-2
|
98%
|
|
Hesperidin methylchalcone is the Citrus original products with powerful antioxidant activity. It can suppresse experimental gout arthritis in mice by inhibiting ...
|
T3775 |
Armepavine
|
524-20-9
|
98%
|
|
Armepavine exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition of NF-κB, JunD and C/EBP pathways. It improves experimental autoimmun...
|
TQ0131 |
Rocaglamide
|
84573-16-0
|
98%
|
|
Rocaglamide, isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB act...
|