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MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T60932 MAO-B-IN-8 1638956-60-1 98.19%
MAO-B-IN-8
MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neu...
T77578 CHBO4 98991-32-3 98.14%
CHBO4
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
T5887 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 22246-18-0 98%
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
T5648 Purpurin 81-54-9 98%
Purpurin
Purpurin (Verantin) was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and anti...
T1025 Tranylcypromine (2-PCPA) hydrochloride 1986-47-6 97.19%
Tranylcypromine (2-PCPA) hydrochloride
Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl), a Monoamine Oxidase inhibitor, is effective in the treatment of major depression, dysthymic disorder, and a...
T16803 RS 8359 105365-76-2 96.03%
RS 8359
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant acti...
T0966 Sennoside A 81-27-6 95.95%
Sennoside A
Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
T1455 Nialamide 51-12-7 90.30%
Nialamide
Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.
T1711 Harmine 442-51-3 100%
Harmine
Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.
T10079 MAO-IN-1 124991-40-8 100%
MAO-IN-1
MAO-IN-1 is a potent monoamine oxidase B (MAO B) inhibitor (IC50: 20 nM) for the study of neurologically related diseases.
T5053 Eprobemide 87940-60-1 100%
Eprobemide
Eprobemide (LIS 630) is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
T0391 Linezolid 165800-03-3 100%
Linezolid
Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria...
TN7211 Tetrahydroharmine 17019-01-1 100%
Tetrahydroharmine
Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Mono...
T67789 Bazinaprine 94011-82-2 100%
Bazinaprine
Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong...
T8589 (±)-Amiflamine 77502-96-6
(±)-Amiflamine
(±)-Amiflamine (2-dimethylphenethylamine) is an inhibitor of reversible MAO-A.
T50055 Milacemide 76990-56-2 98%
Milacemide
Milacemide is a glycine prodrug and MAO-B inhibitor. Milacemide has been studied for its effects on human memory and as a potential treatment for the symptoms of...
T78232 HMAO-B-IN-32 28705-46-6 98%
hMAO-B-IN-32
hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
T26632 AnnH31 241809-12-1 98%
AnnH31
AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the involve...
T0338 Minaprine 25905-77-5 98%
Minaprine
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T6962 Rasagiline Mesylate 161735-79-1 98%
Rasagiline Mesylate
Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
MAO-B-IN-8
T60932
MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neu...
CHBO4
T77578
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
T5887
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
Purpurin
T5648
Purpurin (Verantin) was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and anti...
Tranylcypromine (2-PCPA) hydrochloride
T1025
Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl), a Monoamine Oxidase inhibitor, is effective in the treatment of major depression, dysthymic disorder, and a...
RS 8359
T16803
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant acti...
Sennoside A
T0966
Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
Nialamide
T1455
Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.
Harmine
T1711
Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.
MAO-IN-1
T10079
MAO-IN-1 is a potent monoamine oxidase B (MAO B) inhibitor (IC50: 20 nM) for the study of neurologically related diseases.
Eprobemide
T5053
Eprobemide (LIS 630) is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
Linezolid
T0391
Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria...
Tetrahydroharmine
TN7211
Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Mono...
Bazinaprine
T67789
Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong...
(±)-Amiflamine
T8589
(±)-Amiflamine (2-dimethylphenethylamine) is an inhibitor of reversible MAO-A.
Milacemide
T50055
Milacemide is a glycine prodrug and MAO-B inhibitor. Milacemide has been studied for its effects on human memory and as a potential treatment for the symptoms of...
hMAO-B-IN-32
T78232
hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
AnnH31
T26632
AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the involve...
Minaprine
T0338
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
Rasagiline Mesylate
T6962
Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
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TargetMol