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MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T78232 HMAO-B-IN-32 28705-46-6 99.65%
hMAO-B-IN-32
hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
T0235 Modaline sulfate 2856-75-9 99.65%
Modaline sulfate
Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to...
T2741 Glycyrrhizic acid 1405-86-3 99.62%
Glycyrrhizic acid
Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
T24679 PSB-1434 1619884-65-9 99.61%
PSB-1434
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
T28750 Sembragiline 676479-06-4 99.59%
Sembragiline
Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).
T0084 Moclobemide 71320-77-9 99.59%
Moclobemide
Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
T5678 Lazabemide hydrochloride 103878-83-7 99.56%
Lazabemide hydrochloride
Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki:7.9nM).
T1117 Clorgyline hydrochloride 17780-75-5 99.55%
Clorgyline hydrochloride
Clorgyline hydrochloride (Clorgiline hydrochloride), a white powder, is served as monoamine oxidase inhibitor.
T17211 Vafidemstat 1357362-02-7 99.53%
Vafidemstat
Vafidemstat (ORY-2001) is a selective, orally active lysyl-histone demethylase (LSD1)/MAO-B inhibitor that crosses the blood-brain barrier for the study of neuro...
T60712 MAO-B-IN-17 2890188-81-3 99.41%
MAO-B-IN-17
MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.
T3095 Tyramine 51-67-2 99.4%
Tyramine
Tyramine (Uteramine) is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, bu...
TN1705 Glycyrrhisoflavone 116709-70-7 99.4%
Glycyrrhisoflavone
Glycyrrhisoflavone is a tyrosinase inhibitor with anti-inflammatory effects. Glycyrrhisoflavone inhibits α-glucosidase and monoamine oxidase.
T1747 Tedizolid 856866-72-3 99.37%
Tedizolid
Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of ...
T15023 CX-157 205187-53-7 99.35%
CX-157
CX-157 (KP 157) is a novel monoamine oxidase-A (MAO-A) inhibitor for the study of depression-like neurological disorders and cancer.
T1119 Rasagiline 136236-51-6 99.14%
Rasagiline
Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons di...
TN2004 Obtusin 70588-05-5 99.13%
Obtusin
Obtusin is a natural product.
T1613 Hydralazine hydrochloride 304-20-1 99.1%
Hydralazine hydrochloride
Hydralazine hydrochloride (Apresoline) is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic acti...
T1578 Pargyline hydrochloride 306-07-0 99.08%
Pargyline hydrochloride
Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
T6862 Isatin 91-56-5 99.08%
Isatin
Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.
T68069 Femoxetine 59859-58-4 99.06%
Femoxetine
Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the ...
hMAO-B-IN-32
T78232
hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
Modaline sulfate
T0235
Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to...
Glycyrrhizic acid
T2741
Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
PSB-1434
T24679
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
Sembragiline
T28750
Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).
Moclobemide
T0084
Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
Lazabemide hydrochloride
T5678
Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki:7.9nM).
Clorgyline hydrochloride
T1117
Clorgyline hydrochloride (Clorgiline hydrochloride), a white powder, is served as monoamine oxidase inhibitor.
Vafidemstat
T17211
Vafidemstat (ORY-2001) is a selective, orally active lysyl-histone demethylase (LSD1)/MAO-B inhibitor that crosses the blood-brain barrier for the study of neuro...
MAO-B-IN-17
T60712
MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.
Tyramine
T3095
Tyramine (Uteramine) is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, bu...
Glycyrrhisoflavone
TN1705
Glycyrrhisoflavone is a tyrosinase inhibitor with anti-inflammatory effects. Glycyrrhisoflavone inhibits α-glucosidase and monoamine oxidase.
Tedizolid
T1747
Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of ...
CX-157
T15023
CX-157 (KP 157) is a novel monoamine oxidase-A (MAO-A) inhibitor for the study of depression-like neurological disorders and cancer.
Rasagiline
T1119
Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons di...
Obtusin
TN2004
Obtusin is a natural product.
Hydralazine hydrochloride
T1613
Hydralazine hydrochloride (Apresoline) is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic acti...
Pargyline hydrochloride
T1578
Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
Isatin
T6862
Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.
Femoxetine
T68069
Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the ...
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TargetMol