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Kinesin

A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments, and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport.
Cat. No. Product name CAS No. Purity Chemical Structure
TQ0314 EMD534085 858668-07-2 98%
EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
T4649 Monastrol 254753-54-3 98%
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T17007 TC-Mps1-12 1206170-62-8 98%
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
T14906 CCT251455 1400284-80-1 98%
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
T3434 BAY1217389 1554458-53-5 98%
BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
T12434 PF-2771 2070009-55-9 98%
PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor activity with an IC 50 of 16.1 nM. PF-2771 is used as an...
T11859L Litronesib 910634-41-2 98%
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
T16152 Betamethasone 17-benzoate 22298-29-9 98%
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
T22289 CFI-402257 1610759-22-2 98%
CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.
T12237 NMS-P715 1202055-32-0 98%
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
T3118 Dimethylenastron 863774-58-7 85.65%
Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
T36816 S-trityl-L-Cysteine 2799-07-7 97.02%
S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. ...
T8342 BRD9876 32703-82-5 97.22%
BRD9876 is a selective inhibitor of MM1S growth.
T11155 Eg5 Inhibitor V, trans-24 869304-55-2 97.45%
Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
T8487 Empesertib 1443763-60-7 97.45%
Empesertib is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
T2255 SB-743921 hydrochloride 940929-33-9 98%
SB-743921 is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).
T2689 AZ3146 1124329-14-1 98.03%
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
T6393 ARQ 621 1095253-39-6 98.38%
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
T6209 CW-069 1594094-64-0 98.59%
CW069( IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
T4048 Monastrol 329689-23-8 99.19%
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
EMD534085
TQ0314
EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
Monastrol
T4649
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
TC-Mps1-12
T17007
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
CCT251455
T14906
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
BAY1217389
T3434
BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
PF-2771
T12434
PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor activity with an IC 50 of 16.1 nM. PF-2771 is used as an...
Litronesib
T11859L
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
Betamethasone 17-benzoate
T16152
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
CFI-402257
T22289
CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.
NMS-P715
T12237
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
Dimethylenastron
T3118
Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
S-trityl-L-Cysteine
T36816
S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. ...
BRD9876
T8342
BRD9876 is a selective inhibitor of MM1S growth.
Eg5 Inhibitor V, trans-24
T11155
Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
Empesertib
T8487
Empesertib is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
SB-743921 hydrochloride
T2255
SB-743921 is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).
AZ3146
T2689
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
ARQ 621
T6393
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
CW-069
T6209
CW069( IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
Monastrol
T4048
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
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