T78235 |
4-Phenyl-1H-1,2,3-triazole
|
1680-44-0
|
98%
|
|
4-Phenyl-1H-1,2,3-triazole, an inhibitor of the enzyme IDO1 (IC50: 60 µM), is utilized in cancer research [1].
|
T78687 |
IDO1-IN-21
|
2892432-98-1
|
98%
|
|
IDO1-IN-21 (compound 10m), with an IC50 of 0.64 μM, acts as an IDO1 inhibitor and has demonstrated efficacy in suppressing tumor growth in murine models [1].
|
T78795 |
IDO1/TDO-IN-6
|
2948772-71-0
|
98%
|
|
IDO1/TDO-IN-6 (compound 11) is a dual inhibitor targeting IDO1 and TDO, exhibiting IC50 values of 2.25 μM for IDO1 and 2.89 μM for TDO. The compound further demo...
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T78975 |
IDO1-IN-22
|
2126853-16-3
|
98%
|
|
IDO1-IN-22 (Compound 3) is an inhibitor of IDO1, demonstrating potent activity with biochemical hIDO1 IC50 of 67.4 nM and HeLa hIDO1 IC50 of 17.6 nM. It exhibits...
|
T79189 |
1-Isopropyltryptophan
|
1219485-46-7
|
98%
|
|
1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1].
|
T82082 |
IDO1-IN-23
|
|
98%
|
|
IDO1-IN-23 (compound 41) is a potent inhibitor of human indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 13 μM [1].
|
T8214 |
Kushenol E
|
99119-72-9
|
98%
|
|
Kushenol E (Flemiphilippinin D) is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM, Ki: 9.5 μM), has...
|
T5S0053 |
Coptisine
|
3486-66-6
|
99.91%
|
|
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine t...
|
T4307 |
PF-06840003
|
198474-05-4
|
99.89%
|
|
PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.
|
T4142 |
PCC0208009
|
1668565-74-9
|
99.89%
|
|
PCC0208009 (IDO-IN-2) is an IDO inhibitor.
|
T1806 |
IDO-IN-7
|
1402836-58-1
|
99.87%
|
|
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.
|
T4532 |
Linrodostat
|
1923833-60-6
|
99.84%
|
|
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
|
TQ0071 |
Navoximod
|
1402837-78-8
|
99.81%
|
|
Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).
|
T1847 |
Necrostatin-1
|
4311-88-0
|
99.74%
|
|
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin...
|
T2718 |
Palmatine chloride
|
10605-02-4
|
99.64%
|
|
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
|
T11615 |
IDO-IN-12
|
1888341-29-4
|
99.61%
|
|
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO).
|
T11616 |
IDO-IN-13
|
2291164-02-6
|
99.57%
|
|
IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM).
|
T6543 |
Indoximod
|
110117-83-4
|
99.5%
|
|
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenas...
|
T5S0802 |
Palmatine
|
3486-67-7
|
99.49%
|
|
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palma...
|
T10199 |
GNF-PF-3777
|
77603-42-0
|
99.47%
|
|
GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).
|