TQ0306 |
MLN120B
|
783348-36-7
|
98.86%
|
|
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
|
T6186 |
TRAM-34
|
289905-88-0
|
99.01%
|
|
TRAM-34(Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450....
|
T6165 |
Bardoxolone Methyl
|
218600-53-4
|
99.09%
|
|
Bardoxolone Methyl, an IKK inhibitor, exhibits effective proapoptotic and anti-inflammatory activities.
|
T6326 |
BMS-345541
|
445430-58-0
|
99.29%
|
|
BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
|
T3049 |
TPCA-1
|
507475-17-4
|
99.29%
|
|
TPCA-1 is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzy...
|
T9105 |
NF-κB-IN-1
|
1227098-15-8
|
99.29%
|
|
NF-κB-IN-1 is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κ...
|
T10477 |
BAY-985
|
2409479-29-2
|
99.3%
|
|
BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with an...
|
T6771 |
AZD3264
|
1609281-86-8
|
99.42%
|
|
AZD3264 is a new type IKK2 inhibitor.
|
T1934 |
Bay 11-7085
|
196309-76-9
|
99.43%
|
|
BAY 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
|
T8910 |
2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
|
4815-35-4
|
99.44%
|
|
2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.
|
T1639 |
Amlexanox
|
68302-57-8
|
99.56%
|
|
Amlexanox is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast...
|
T1830 |
BX795
|
702675-74-9
|
99.57%
|
|
BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respect...
|
T6176 |
IKK 16
|
873225-46-8
|
99.61%
|
|
IKK-16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
|
T3094 |
PS-1145
|
431898-65-6
|
99.63%
|
|
PS-1145 is a specific IKK inhibitor with IC50 of 88 nM.
|
T7081 |
CCCP
|
555-60-2
|
99.64%
|
|
CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochondr...
|
T6141 |
IMD-0354
|
978-62-1
|
99.65%
|
|
IMD-0354 is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.
|
T25465 |
GS143
|
916232-21-8
|
99.72%
|
|
GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and t...
|
T5S0993 |
Kurarinone
|
34981-26-5
|
99.72%
|
|
Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong ...
|
T2765 |
Rosmarinic acid
|
20283-92-5
|
99.73%
|
|
Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive ...
|
T3736 |
Olivetol
|
500-66-3
|
99.74%
|
|
Olivetol (5-pentylresorcinol, 5-pentyl-1,3-benzenediol) is an organic compound found in certain species of lichen; it is also a precursor in various syntheses of...
|