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Hydroxylase

Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound. In biochemistry, hydroxylation reactions are often facilitated by enzymes called hydroxylases. Hydroxylation is the first step in the oxidative degradation of organic compounds in air. It is extremely important in detoxification since hydroxylation converts lipophilic compounds into water-soluble (hydrophilic) products that are more readily removed by the kidneys or liver and excreted. Some drugs (for example, steroids) are activated or deactivated by hydroxylation.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T13383 Zamicastat 1080028-80-3 97.43%
Zamicastat
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73....
T10142L P-Ethynylphenylalanine hydrochloride 188640-63-3
p-Ethynylphenylalanine hydrochloride
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanin...
T6604 Nepicastat hydrochloride 170151-24-3 98%
Nepicastat hydrochloride
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50...
T11897 Telotristat ethyl 1033805-22-9 98%
Telotristat ethyl
Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
T61214 EWP 815 20231-01-0 98%
EWP 815
EWP 815 is a disulfiram analogue that functions as a powerful inhibitor of Ins(1,4) P 2 phosphatase, Ins(1,4,5) P 3 5-phosphatase, and dopamine β-hydroxylase act...
Zamicastat
T13383
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73....
p-Ethynylphenylalanine hydrochloride
T10142L
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanin...
Nepicastat hydrochloride
T6604
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50...
Telotristat ethyl
T11897
Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
EWP 815
T61214
EWP 815 is a disulfiram analogue that functions as a powerful inhibitor of Ins(1,4) P 2 phosphatase, Ins(1,4,5) P 3 5-phosphatase, and dopamine β-hydroxylase act...
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TargetMol