Histone Acetyltransferase

Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA to form ε-N-acetyllysine. DNA is wrapped around histones, and, by transferring an acetyl group to the histones, genes can be turned on and off. In general, histone acetylation increases gene expression.

Cat. No.	Product name	CAS No.	Purity
TN1150	Procyanidin B3	23567-23-9	98%
TN1150	Procyanidin B3(B3) is a procyanidin dimer that is widely studied due to its high abundance in the human diet and antioxidant activity.
T6389	Anacardic Acid	16611-84-0	98%
T6389	Anacardic Acid is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial acti...
T3499	Remodelin	949912-58-7	98%
T3499	Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.
T6133	Remodelin hydrobromide	1622921-15-6	98%
T6133	Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
T6908	NSC 228155	113104-25-9	98%
T6908	NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
T7856	Naphthol AS-E	92-78-4	98%
T7856	nAS-E is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.
T60558	NSC 694623	907957-34-0	98%
T60558	NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with IC50 of 15.9 μM against recombinant HAT p300/CBP associated factor (PCAF). NSC 694623 shows...
T12098	MOZ-IN-2	2055397-88-9	98%
T12098	MOZ-IN-2 is an protein MOZ inhibitor(IC50 of 125 μM).
T6811	CPI-637	1884712-47-3	98%
T6811	CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.
T4362	WM-8014	2055397-18-5	98%
T4362	MOZ-IN-3 is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.
T0065	Acetaminophen	103-90-2	98%
T0065	Analgesic antipyretic derivative of acetanilide. Acetaminophen has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, bloo...
T23095	NU 9056	1450644-28-6	98%
T23095	NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM. NU 9056 blocks DNA damage response and inhibits protein a...