T5126 |
Glecaprevir
|
1365970-03-1
|
99.16%
|
|
Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).
|
T4988 |
Boceprevir
|
394730-60-0
|
99.16%
|
|
Boceprevir is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-...
|
TQ0122L |
VCH-916 free acid(1200133-34-1 free base)
|
914778-92-0
|
99.19%
|
|
VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.
|
T2117 |
PSI-6206
|
863329-66-2
|
99.33%
|
|
PSI-6206 (RO2433) is a selective HCV RNA polymerase inhibitor.
|
T7607 |
PSI-6130
|
817204-33-4
|
99.36%
|
|
PSI-6130 is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.
|
T16088 |
MK-0608
|
443642-29-3
|
99.42%
|
|
MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).
|
T21537L |
TMC647055 Choline Hydroxide Salt
|
T21537L
|
99.44%
|
|
TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. ...
|
T7158 |
Ombitasvir
|
1258226-87-7
|
99.56%
|
|
Ombitasvir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against H...
|
T3226 |
Paritaprevir
|
1221573-85-8
|
99.57%
|
|
Paritaprevir is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3...
|
T3810 |
Saikosaponin B2
|
58316-41-9
|
99.59%
|
|
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2...
|
T3489 |
Dasabuvir
|
1132935-63-7
|
99.62%
|
|
Dasabuvir is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity...
|
T3821 |
Deapioplatycodin D
|
78763-58-3
|
99.64%
|
|
Deapi-platycodin and platycodin D can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extrac...
|
T2770 |
Gentiopicroside
|
20831-76-9
|
99.64%
|
|
Gentiopicroside, a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22...
|
T3001 |
Honokiol
|
35354-74-6
|
99.65%
|
|
Honokiol is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
|
T3444 |
Merimepodib
|
198821-22-6
|
99.66%
|
|
Merimepodib is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
|
T15282 |
Filibuvir
|
877130-28-4
|
99.68%
|
|
Filibuvir is a selective and noncovalent inhibitor of HCV NS5B RNA-dependent RNA polymerase. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM....
|
T9341 |
Bemnifosbuvir
|
1998705-64-8
|
99.69%
|
|
Bemnifosbuvir is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.
|
T2047 |
AG-1478
|
153436-53-4
|
99.71%
|
|
AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor.
|
T5127 |
ABT530
|
1353900-92-1
|
99.73%
|
|
ABT-530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6.
|
T9331 |
Bemnifosbuvir hemisulfate
|
2241337-84-6
|
99.74%
|
|
Bemnifosbuvir hemisulfate is a potent inhibitor of HCV virus replication.
|