HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.

Cat. No.	Product name	CAS No.	Purity
TN1703	Glycyrin	66056-18-6	98%
TN1703	Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
TN3809	Dehydrojuncusol	117824-04-1	98%
TN3809	Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is acti...
TN4404	Ladanein	10176-71-3	98%
TN4404	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radic...
T5539	GS-443902	1355149-45-9	98%
T5539	GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
T14095	ACH-806	870142-71-5	98%
T14095	ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
TN5079	Sulochrin	519-57-3	98%
TN5079	Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotox...
T13281	Valopicitabine	640281-90-9	98%
T13281	Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic ...
TN1034	Sennidin B	517-44-2	98%
TN1034	Sennidin B stimulates glucose incorporation in rat adipocytes.
T10067	2',5-Difluoro-2'-deoxycytidine	581772-30-7	98%
T10067	2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.
T12956	Sofosbuvir impurity A	1496552-16-9	98%
T12956	Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
T14555	BI-1230	849022-32-8	98%
T14555	BI-1230 is potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication and it is also highly selective against other serine/cysteine protea...
TN5263	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one	569-83-5	98%
TN5263	Xanthohumol, prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus. Xanthohumol is effective against HIV-1 and...
TN3438	Arborinine	5489-57-6	98%
TN3438	Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0....
T15235	Enocitabine	55726-47-1	98%
T15235	Enocitabine, a nucleoside analog, is a potent DNA replication inhibitor and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus...
T11539	HCV-IN-29	1009119-83-8	98%
T11539	HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.
T9717	Chlorcyclizine	82-93-9	98%
T9717	CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.
T38237	2′-O-Methylcytidine	2140-72-9	98%
T38237	2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
T25268L	Coblopasvir dihydrochloride	1966138-53-3	98%
T25268L	Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.
T38375	2-Nonylquinolin-4(1H)-one	55396-45-7	98%
T38375	2-Nonylquinolin-4(1H)-one reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml.
T14489	Azvudine	1011529-10-4	100%
T14489	Azvudine is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strai...