T3464 |
PHCCC
|
179068-02-1
|
99.31%
|
|
PHCCC is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGl...
|
T0326L |
L-Glutamine
|
56-85-9
|
99.36%
|
|
L-glutamine, a non-essential amino acid, is synthesized from glutamic acid and ammonia.
|
T12717 |
Basimglurant
|
802906-73-6
|
99.38%
|
|
Basimglurant is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).
|
T15090 |
Decoglurant
|
911115-16-7
|
99.39%
|
|
Decoglurant is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.
|
T22641 |
CDPPB
|
781652-57-1
|
99.39%
|
|
CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
|
T5512 |
JNJ16259685
|
409345-29-5
|
99.39%
|
|
JNJ16259685 is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19 nM.
|
T3473 |
(S)-ATPO
|
252930-37-3
|
99.41%
|
|
ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
|
TP2111L |
TAT-GluA2 3Y acetate(1404188-93-7 free base)
|
TP2111L
|
99.43%
|
|
TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in ra...
|
T15275 |
Fenobam
|
57653-26-6
|
99.44%
|
|
Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and n...
|
T2811 |
Harmine hydrochloride
|
343-27-1
|
99.45%
|
|
Harmine hydrochloride is extracted from Peganum Harmala Genus.
|
T6871 |
L-Glutamic acid monosodium salt
|
142-47-2
|
99.45%
|
|
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
|
T23515 |
VU-29
|
890764-36-0
|
99.47%
|
|
VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC...
|
T3478 |
Ro 67-7476
|
298690-60-5
|
99.48%
|
|
Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 ...
|
T8779 |
HBT1
|
489408-02-8
|
99.48%
|
|
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons....
|
T8626 |
4-oxo-1,4-dihydroquinoline-2-carboxylic acid
|
13593-94-7
|
99.49%
|
|
4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
|
T10432L |
AZD-8529 mesylate
|
1314217-69-0
|
99.5%
|
|
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulato...
|
T3484 |
Trans-ACPD
|
67684-64-4
|
99.53%
|
|
(±)-trans-ACPD is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. (±)-trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor); ...
|
T11393 |
GET73
|
202402-01-5
|
99.54%
|
|
GET73 is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
|
T11032 |
DHPG
|
146255-66-5
|
99.55%
|
|
DHPG ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D. It is an amino acid that can be used as a selective and potent agonist for Gr...
|
T3565 |
VU0155041
|
1093757-42-6
|
99.56%
|
|
UV0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
|