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GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.
Cat. No. Product name CAS No. Purity Chemical Structure
T3464 PHCCC 179068-02-1 99.31%
PHCCC is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGl...
T0326L L-Glutamine 56-85-9 99.36%
L-glutamine, a non-essential amino acid, is synthesized from glutamic acid and ammonia.
T12717 Basimglurant 802906-73-6 99.38%
Basimglurant is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).
T15090 Decoglurant 911115-16-7 99.39%
Decoglurant is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.
T22641 CDPPB 781652-57-1 99.39%
CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
T5512 JNJ16259685 409345-29-5 99.39%
JNJ16259685 is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19 nM.
T3473 (S)-ATPO 252930-37-3 99.41%
ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
TP2111L TAT-GluA2 3Y acetate(1404188-93-7 free base) TP2111L 99.43%
TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in ra...
T15275 Fenobam 57653-26-6 99.44%
Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and n...
T2811 Harmine hydrochloride 343-27-1 99.45%
Harmine hydrochloride is extracted from Peganum Harmala Genus.
T6871 L-Glutamic acid monosodium salt 142-47-2 99.45%
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
T23515 VU-29 890764-36-0 99.47%
VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC...
T3478 Ro 67-7476 298690-60-5 99.48%
Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 ...
T8779 HBT1 489408-02-8 99.48%
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons....
T8626 4-oxo-1,4-dihydroquinoline-2-carboxylic acid 13593-94-7 99.49%
4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
T10432L AZD-8529 mesylate 1314217-69-0 99.5%
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulato...
T3484 Trans-ACPD 67684-64-4 99.53%
(±)-trans-ACPD is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. (±)-trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor); ...
T11393 GET73 202402-01-5 99.54%
GET73 is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
T11032 DHPG 146255-66-5 99.55%
DHPG ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D. It is an amino acid that can be used as a selective and potent agonist for Gr...
T3565 VU0155041 1093757-42-6 99.56%
UV0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
PHCCC
T3464
PHCCC is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGl...
L-Glutamine
T0326L
L-glutamine, a non-essential amino acid, is synthesized from glutamic acid and ammonia.
Basimglurant
T12717
Basimglurant is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).
Decoglurant
T15090
Decoglurant is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.
CDPPB
T22641
CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
JNJ16259685
T5512
JNJ16259685 is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19 nM.
(S)-ATPO
T3473
ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
TAT-GluA2 3Y acetate(1404188-93-7 free base)
TP2111L
TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in ra...
Fenobam
T15275
Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and n...
Harmine hydrochloride
T2811
Harmine hydrochloride is extracted from Peganum Harmala Genus.
L-Glutamic acid monosodium salt
T6871
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
VU-29
T23515
VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC...
Ro 67-7476
T3478
Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 ...
HBT1
T8779
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons....
4-oxo-1,4-dihydroquinoline-2-carboxylic acid
T8626
4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
AZD-8529 mesylate
T10432L
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulato...
trans-ACPD
T3484
(±)-trans-ACPD is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. (±)-trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor); ...
GET73
T11393
GET73 is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
DHPG
T11032
DHPG ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D. It is an amino acid that can be used as a selective and potent agonist for Gr...
VU0155041
T3565
UV0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
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