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GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.
Cat. No. Product name CAS No. Purity Chemical Structure
T3482 CFMTI 864864-17-5 98.61%
CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000...
T0024 Primidone 125-33-7 98.68%
Primidone is an anticonvulsant of the pyrimidinedione class.
T4573 Cyclothiazide 2259-96-3 98.74%
Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its r...
T0313 Evans blue 314-13-6 98.85%
Evans blue is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
T13318 VU0650786 1809085-30-0 98.96%
VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with ant...
T9970 1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 374548-18-2 98.99%
1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile is a positive allosteric modulator of mGluR3 and can be used in studies about the treatmen...
T6022 LY404039 635318-11-5 99.03%
LY404039 is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
T23003 ML337 1443118-44-2 99.09%
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
T3451 JNJ-42153605 1254977-87-1 99.13%
JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).
T23291 (S)-3-Hydroxyphenylglycine 71301-82-1 99.18%
group I metabotropic glutamate receptors agonist
T2053 ADX-47273 851881-60-2 99.18%
ADX-47273 is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
T23514 VU-1545 890764-63-3 99.24%
VU 1545 is mGlu5 positive allosteric modulator.
T8457 NPS2390 226878-01-9 99.24%
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
T16816 S 18986 175340-20-2 99.25%
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rode...
T4500 ADX88178 1235318-89-4 99.26%
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
T23008L MMPIP hydrochloride 1215566-78-1 99.26%
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system ...
T5083 L-Cysteic acid monohydrate 23537-25-9 99.28%
L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
T1884 CX516 154235-83-3 99.29%
Ampalex (Ampakine CX516; CX516; BDP 12), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, ...
T6598 MPEP 96206-92-7 99.31%
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
T1324 O-Phospho-L-serine 407-41-0 99.31%
Phosphoserine is the phosphoric acid ester of serine.
CFMTI
T3482
CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000...
Primidone
T0024
Primidone is an anticonvulsant of the pyrimidinedione class.
Cyclothiazide
T4573
Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its r...
Evans blue
T0313
Evans blue is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
VU0650786
T13318
VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with ant...
1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile
T9970
1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile is a positive allosteric modulator of mGluR3 and can be used in studies about the treatmen...
LY404039
T6022
LY404039 is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
ML337
T23003
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
JNJ-42153605
T3451
JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).
(S)-3-Hydroxyphenylglycine
T23291
group I metabotropic glutamate receptors agonist
ADX-47273
T2053
ADX-47273 is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
VU-1545
T23514
VU 1545 is mGlu5 positive allosteric modulator.
NPS2390
T8457
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
S 18986
T16816
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rode...
ADX88178
T4500
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
MMPIP hydrochloride
T23008L
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system ...
L-Cysteic acid monohydrate
T5083
L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
CX516
T1884
Ampalex (Ampakine CX516; CX516; BDP 12), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, ...
MPEP
T6598
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
O-Phospho-L-serine
T1324
Phosphoserine is the phosphoric acid ester of serine.
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