GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T3482	CFMTI	864864-17-5	98.61%
T3482	CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000...
T0024	Primidone	125-33-7	98.68%
T0024	Primidone is an anticonvulsant of the pyrimidinedione class.
T4573	Cyclothiazide	2259-96-3	98.74%
T4573	Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its r...
T0313	Evans blue	314-13-6	98.85%
T0313	Evans blue is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
T13318	VU0650786	1809085-30-0	98.96%
T13318	VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with ant...
T9970	1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile	374548-18-2	98.99%
T9970	1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile is a positive allosteric modulator of mGluR3 and can be used in studies about the treatmen...
T6022	LY404039	635318-11-5	99.03%
T6022	LY404039 is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
T23003	ML337	1443118-44-2	99.09%
T23003	ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
T3451	JNJ-42153605	1254977-87-1	99.13%
T3451	JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).
T23291	(S)-3-Hydroxyphenylglycine	71301-82-1	99.18%
T23291	group I metabotropic glutamate receptors agonist
T2053	ADX-47273	851881-60-2	99.18%
T2053	ADX-47273 is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
T23514	VU-1545	890764-63-3	99.24%
T23514	VU 1545 is mGlu5 positive allosteric modulator.
T8457	NPS2390	226878-01-9	99.24%
T8457	NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
T16816	S 18986	175340-20-2	99.25%
T16816	S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rode...
T4500	ADX88178	1235318-89-4	99.26%
T4500	ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
T23008L	MMPIP hydrochloride	1215566-78-1	99.26%
T23008L	MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system ...
T5083	L-Cysteic acid monohydrate	23537-25-9	99.28%
T5083	L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
T1884	CX516	154235-83-3	99.29%
T1884	Ampalex (Ampakine CX516; CX516; BDP 12), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, ...
T6598	MPEP	96206-92-7	99.31%
T6598	MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
T1324	O-Phospho-L-serine	407-41-0	99.31%
T1324	Phosphoserine is the phosphoric acid ester of serine.