T3482 |
CFMTI
|
864864-17-5
|
98.61%
|
|
CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000...
|
T0024 |
Primidone
|
125-33-7
|
98.68%
|
|
Primidone is an anticonvulsant of the pyrimidinedione class.
|
T4573 |
Cyclothiazide
|
2259-96-3
|
98.74%
|
|
Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its r...
|
T0313 |
Evans blue
|
314-13-6
|
98.85%
|
|
Evans blue is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
|
T13318 |
VU0650786
|
1809085-30-0
|
98.96%
|
|
VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with ant...
|
T9970 |
1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile
|
374548-18-2
|
98.99%
|
|
1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile is a positive allosteric modulator of mGluR3 and can be used in studies about the treatmen...
|
T6022 |
LY404039
|
635318-11-5
|
99.03%
|
|
LY404039 is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
|
T23003 |
ML337
|
1443118-44-2
|
99.09%
|
|
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
|
T3451 |
JNJ-42153605
|
1254977-87-1
|
99.13%
|
|
JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).
|
T23291 |
(S)-3-Hydroxyphenylglycine
|
71301-82-1
|
99.18%
|
|
group I metabotropic glutamate receptors agonist
|
T2053 |
ADX-47273
|
851881-60-2
|
99.18%
|
|
ADX-47273 is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
|
T23514 |
VU-1545
|
890764-63-3
|
99.24%
|
|
VU 1545 is mGlu5 positive allosteric modulator.
|
T8457 |
NPS2390
|
226878-01-9
|
99.24%
|
|
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
|
T16816 |
S 18986
|
175340-20-2
|
99.25%
|
|
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rode...
|
T4500 |
ADX88178
|
1235318-89-4
|
99.26%
|
|
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
|
T23008L |
MMPIP hydrochloride
|
1215566-78-1
|
99.26%
|
|
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system ...
|
T5083 |
L-Cysteic acid monohydrate
|
23537-25-9
|
99.28%
|
|
L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
|
T1884 |
CX516
|
154235-83-3
|
99.29%
|
|
Ampalex (Ampakine CX516; CX516; BDP 12), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, ...
|
T6598 |
MPEP
|
96206-92-7
|
99.31%
|
|
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
|
T1324 |
O-Phospho-L-serine
|
407-41-0
|
99.31%
|
|
Phosphoserine is the phosphoric acid ester of serine.
|