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GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.
Cat. No. Product name CAS No. Purity Chemical Structure
T3483 FTIDC 873551-53-2 94.58%
FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibiti...
T22730 DL-AP3 20263-06-3 95%
DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
T21747 VU0483605 1623101-11-0 97.03%
VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
TP1943L1 Pep2-EVKI acetate(1315378-67-6 free base) TP1943L1 97.63%
Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA rece...
T4113 NBQX 118876-58-7 97.66%
Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
T21935L AMN082 free base 83027-13-8 97.76%
AMN082 is a metabotropic glutamate receptor 7 allosteric agonist.
T3010 Xanthurenic Acid 59-00-7 97.96%
Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGl...
T3539 Lu AF21934 1445605-23-1 97.96%
Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).
T5884 Chelidamic acid 138-60-3 98%
Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.
T7292 FITM 932737-65-0 98%
FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).
T7304 DNQX 2379-57-9 98%
DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
T0675 Topiramate 97240-79-4 98%
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T7515 MTEP hydrochloride 1186195-60-7 98%
MTEP hydrochloride is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)
T0256 Citric acid trilithium salt tetrahydrate 6080-58-6 98%
Lithium Citrate, the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and me...
T7579 1-BCP 34023-62-6 98%
1-BCP is a centrally active drug that modulates AMPA receptor gated currents.
T7178 CNQX 115066-14-3 98%
CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
T3486 3-MATIDA 518357-51-2 98.41%
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4...
T8434 SIB-1757 31993-01-8 98.49%
SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)
T9021 Ro0711401 714971-87-6 98.54%
Ro0711401 is an agonist of mGlu1 receptor.
T16524 Philanthotoxin 74 dihydrochloride 1227301-51-0 98.6%
Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.
FTIDC
T3483
FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibiti...
DL-AP3
T22730
DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
VU0483605
T21747
VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
pep2-EVKI acetate(1315378-67-6 free base)
TP1943L1
Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA rece...
NBQX
T4113
Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
AMN082 free base
T21935L
AMN082 is a metabotropic glutamate receptor 7 allosteric agonist.
Xanthurenic Acid
T3010
Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGl...
Lu AF21934
T3539
Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).
Chelidamic acid
T5884
Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.
FITM
T7292
FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).
DNQX
T7304
DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
Topiramate
T0675
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
MTEP hydrochloride
T7515
MTEP hydrochloride is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)
Citric acid trilithium salt tetrahydrate
T0256
Lithium Citrate, the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and me...
1-BCP
T7579
1-BCP is a centrally active drug that modulates AMPA receptor gated currents.
CNQX
T7178
CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
3-MATIDA
T3486
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4...
SIB-1757
T8434
SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)
Ro0711401
T9021
Ro0711401 is an agonist of mGlu1 receptor.
Philanthotoxin 74 dihydrochloride
T16524
Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.
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