GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T3483	FTIDC	873551-53-2	94.58%
T3483	FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibiti...
T22730	DL-AP3	20263-06-3	95%
T22730	DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
T21747	VU0483605	1623101-11-0	97.03%
T21747	VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
TP1943L1	Pep2-EVKI acetate(1315378-67-6 free base)	TP1943L1	97.63%
TP1943L1	Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA rece...
T4113	NBQX	118876-58-7	97.66%
T4113	Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
T21935L	AMN082 free base	83027-13-8	97.76%
T21935L	AMN082 is a metabotropic glutamate receptor 7 allosteric agonist.
T3010	Xanthurenic Acid	59-00-7	97.96%
T3010	Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGl...
T3539	Lu AF21934	1445605-23-1	97.96%
T3539	Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).
T5884	Chelidamic acid	138-60-3	98%
T5884	Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.
T7292	FITM	932737-65-0	98%
T7292	FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).
T7304	DNQX	2379-57-9	98%
T7304	DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
T0675	Topiramate	97240-79-4	98%
T0675	Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T7515	MTEP hydrochloride	1186195-60-7	98%
T7515	MTEP hydrochloride is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)
T0256	Citric acid trilithium salt tetrahydrate	6080-58-6	98%
T0256	Lithium Citrate, the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and me...
T7579	1-BCP	34023-62-6	98%
T7579	1-BCP is a centrally active drug that modulates AMPA receptor gated currents.
T7178	CNQX	115066-14-3	98%
T7178	CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
T3486	3-MATIDA	518357-51-2	98.41%
T3486	3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4...
T8434	SIB-1757	31993-01-8	98.49%
T8434	SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)
T9021	Ro0711401	714971-87-6	98.54%
T9021	Ro0711401 is an agonist of mGlu1 receptor.
T16524	Philanthotoxin 74 dihydrochloride	1227301-51-0	98.6%
T16524	Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.