GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T3478	Ro 67-7476	298690-60-5	99.48%
T3478	Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 ...
T23515	VU-29	890764-36-0	99.47%
T23515	VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC...
T2811	Harmine hydrochloride	343-27-1	99.45%
T2811	Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.
T15275	Fenobam	57653-26-6	99.44%
T15275	Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and n...
TP2111L	TAT-GluA2 3Y acetate(1404188-93-7 free base)	TP2111L	99.43%
TP2111L	TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis.Systemic administration of Tat-GluA2(3Y) during the induction phase of d-amphetamine blocked ma...
T4113	NBQX	118876-58-7	99.42%
T4113	NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
T3473	(S)-ATPO	252930-37-3	99.41%
T3473	(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
T15090	Decoglurant	911115-16-7	99.39%
T15090	Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.
T5512	JNJ16259685	409345-29-5	99.39%
T5512	JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19 ...
T22641	CDPPB	781652-57-1	99.39%
T22641	CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
T12717	Basimglurant	802906-73-6	99.38%
T12717	Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).
T15816	LY341495	201943-63-7	99.37%
T15816	LY341495 is a potent metabotropic glutamate receptor antagonist that exhibits high activity against a wide range of glutamate receptor subtypes and can be used f...
T0326L	L-Glutamine	56-85-9	99.36%
T0326L	L-Glutamine (L-Glutamic acid 5-amide) , a non-essential amino acid, is synthesized from glutamic acid and ammonia.
T27854	LSN2463359	1401031-52-4	99.36%
T27854	LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
T27947L	LY339434 HCl		99.32%
T27947L	LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA) rec...
T7304	DNQX	2379-57-9	99.32%
T7304	DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
T3464	PHCCC	179068-02-1	99.31%
T3464	PHCCC ((-) PHCCC) is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mG...
T6598	MPEP	96206-92-7	99.31%
T6598	MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
T1324	O-Phospho-L-serine	407-41-0	99.31%
T1324	O-Phospho-L-serine (Phosphoserine) is the phosphoric acid ester of serine.
T1884	CX516	154235-83-3	99.29%
T1884	CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and mild c...