T3403 |
Glabridin
|
59870-68-7
|
98%
|
|
Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-gluc...
|
T1065 |
Baclofen
|
1134-47-0
|
98%
|
|
Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen act...
|
T8036 |
6-Methylflavone
|
29976-75-8
|
98%
|
|
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
|
T4590 |
(+)-Kavain
|
500-64-1
|
98%
|
|
Kawain is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
|
T26891 |
BPDBA
|
312281-74-6
|
98%
|
|
|
T7699 |
AZD7325
|
942437-37-8
|
98%
|
|
AZD-7325 is a GABA-Aα2,3 -selective receptor modulator.
|
T0349 |
Riluzole
|
1744-22-5
|
98%
|
|
Riluzole is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LA...
|
T5330 |
Fluralaner
|
864731-61-3
|
98%
|
|
Fluralaner is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes ...
|
T1240 |
Flumazenil
|
78755-81-4
|
98%
|
|
Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS),...
|
T0710 |
L-Cycloserine
|
339-72-0
|
98%
|
|
L-cycloserine irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in incre...
|
T13536 |
Afoxolaner
|
1093861-60-9
|
98%
|
|
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA...
|
T8639 |
Phenibut (hydrochloride)
|
3060-41-1
|
98%
|
|
Phenibut (hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates d...
|
T5375 |
Loreclezole
|
117857-45-1
|
98%
|
|
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
|
T2S1464 |
Thiocolchicoside
|
602-41-5
|
98%
|
|
Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonis...
|
T3644 |
U93631
|
152273-12-6
|
98%
|
|
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GAB...
|
T0715 |
Chlormezanone
|
80-77-3
|
98%
|
|
Chlormezanone is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
|
T2339 |
Apalutamide
|
956104-40-8
|
98%
|
|
Apalutamide is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
|
T8572 |
CL 218872
|
66548-69-4
|
98%
|
|
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 n...
|
T1396 |
Bemegride
|
64-65-3
|
98%
|
|
Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.
|
T2850 |
Bicuculline
|
485-49-4
|
98%
|
|
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated...
|