GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
T3403	Glabridin	59870-68-7	98%
T3403	Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-gluc...
T1065	Baclofen	1134-47-0	98%
T1065	Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen act...
T8036	6-Methylflavone	29976-75-8	98%
T8036	6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
T4590	(+)-Kavain	500-64-1	98%
T4590	Kawain is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
T26891	BPDBA	312281-74-6	98%
T26891
T7699	AZD7325	942437-37-8	98%
T7699	AZD-7325 is a GABA-Aα2,3 -selective receptor modulator.
T0349	Riluzole	1744-22-5	98%
T0349	Riluzole is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LA...
T5330	Fluralaner	864731-61-3	98%
T5330	Fluralaner is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes ...
T1240	Flumazenil	78755-81-4	98%
T1240	Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS),...
T0710	L-Cycloserine	339-72-0	98%
T0710	L-cycloserine irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in incre...
T13536	Afoxolaner	1093861-60-9	98%
T13536	Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA...
T8639	Phenibut (hydrochloride)	3060-41-1	98%
T8639	Phenibut (hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates d...
T5375	Loreclezole	117857-45-1	98%
T5375	Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
T2S1464	Thiocolchicoside	602-41-5	98%
T2S1464	Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonis...
T3644	U93631	152273-12-6	98%
T3644	GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GAB...
T0715	Chlormezanone	80-77-3	98%
T0715	Chlormezanone is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
T2339	Apalutamide	956104-40-8	98%
T2339	Apalutamide is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
T8572	CL 218872	66548-69-4	98%
T8572	CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 n...
T1396	Bemegride	64-65-3	98%
T1396	Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.
T2850	Bicuculline	485-49-4	98%
T2850	Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated...