GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
T17144	TPA 023	252977-51-8	98%
T17144	TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).
T23039	N-Arachidonyl-GABA	128201-89-8	98%
T23039	N-Arachidonyl-GABA (NA-GABA) is a novel active fatty amino acid related to anandamide (ANA) found in cattle. NA-GABA has analgesic activity
T0627	β-Alanine	107-95-9	98%
T0627	β-Alanine is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating ...
T0883	Tramiprosate	3687-18-1	98%
T0883	Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. H...
T1602	Valproic acid sodium salt	1069-66-5	98%
T1602	Valproate Sodium is the sodium salt form of valproic acid with anti-epileptic activity. Valproate sodium is converted into its active form, valproate ion, in blo...
T7557	Guvacine hydrochloride	6027-91-4	98%
T7557	Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
T10618	Broflanilide	1207727-04-5	98%
T10618	Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL ...
T38205	3-Aminopropylphosphonic Acid	13138-33-5	98%
T38205	3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding as...
T23339	SCS	3232-36-8	98%
T23339	GABAA receptor antagonist
T11277	FG 7142	78538-74-6	98%
T11277	FG 7142 also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and ca...
T22301	L-838417 D9	1213669-91-0	98%
T22301	L-838417 is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
T23104	Ocinaplon	96604-21-6	98%
T23104	GABAA receptors modulator
TN1217	2'-O-Methylisoliquiritigenin	51828-10-5	98%
TN1217	2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.
T12930	SKF89976A hydrochloride	85375-15-1	98%
T12930	SKF89976A hydrochloride is a selective inhibitor of GABA transporter (GAT-1)(IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, re...
T15212	Emamectin Benzoate	155569-91-8	98%
T15212	Emamectin Benzoate, by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as ...
T3318	Wogonoside	51059-44-0	98%
T3318	Wogonoside acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.
T11822	LAU159	2055050-87-6	98%
T11822	LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).
T7794	Zuranolone	1632051-40-1	98%
T7794	Zuranolone is an agonist of GABAA receptor.
T2775	Baicalin	21967-41-9	98%
T2775	Baicalin is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.
T1860	Imepitoin	188116-07-6	98%
T1860	AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.