T17144 |
TPA 023
|
252977-51-8
|
98%
|
|
TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).
|
T23039 |
N-Arachidonyl-GABA
|
128201-89-8
|
98%
|
|
N-Arachidonyl-GABA (NA-GABA) is a novel active fatty amino acid related to anandamide (ANA) found in cattle. NA-GABA has analgesic activity
|
T0627 |
β-Alanine
|
107-95-9
|
98%
|
|
β-Alanine is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating ...
|
T0883 |
Tramiprosate
|
3687-18-1
|
98%
|
|
Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. H...
|
T1602 |
Valproic acid sodium salt
|
1069-66-5
|
98%
|
|
Valproate Sodium is the sodium salt form of valproic acid with anti-epileptic activity. Valproate sodium is converted into its active form, valproate ion, in blo...
|
T7557 |
Guvacine hydrochloride
|
6027-91-4
|
98%
|
|
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
|
T10618 |
Broflanilide
|
1207727-04-5
|
98%
|
|
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL ...
|
T38205 |
3-Aminopropylphosphonic Acid
|
13138-33-5
|
98%
|
|
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding as...
|
T23339 |
SCS
|
3232-36-8
|
98%
|
|
GABAA receptor antagonist
|
T11277 |
FG 7142
|
78538-74-6
|
98%
|
|
FG 7142 also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and ca...
|
T22301 |
L-838417 D9
|
1213669-91-0
|
98%
|
|
L-838417 is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
|
T23104 |
Ocinaplon
|
96604-21-6
|
98%
|
|
GABAA receptors modulator
|
TN1217 |
2'-O-Methylisoliquiritigenin
|
51828-10-5
|
98%
|
|
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.
|
T12930 |
SKF89976A hydrochloride
|
85375-15-1
|
98%
|
|
SKF89976A hydrochloride is a selective inhibitor of GABA transporter (GAT-1)(IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, re...
|
T15212 |
Emamectin Benzoate
|
155569-91-8
|
98%
|
|
Emamectin Benzoate, by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as ...
|
T3318 |
Wogonoside
|
51059-44-0
|
98%
|
|
Wogonoside acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.
|
T11822 |
LAU159
|
2055050-87-6
|
98%
|
|
LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).
|
T7794 |
Zuranolone
|
1632051-40-1
|
98%
|
|
Zuranolone is an agonist of GABAA receptor.
|
T2775 |
Baicalin
|
21967-41-9
|
98%
|
|
Baicalin is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.
|
T1860 |
Imepitoin
|
188116-07-6
|
98%
|
|
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
|