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GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T13690 Etifoxine hydrochloride 56776-32-0 99.25%
Etifoxine hydrochloride
Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug. Unlike benzodiazepines, Etifoxine hydrochloride appears to produce i...
T26891 BPDBA 312281-74-6 99.24%
BPDBA
BPDBA is a useful organic compound for research related to life sciences. The catalog number is T26891 and the CAS number is 312281-74-6.
T2407 Tiagabine 115103-54-3 99.24%
Tiagabine
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Acti...
T2983 3,4,5-Trimethoxycinnamic acid 90-50-6 99.19%
3,4,5-Trimethoxycinnamic acid
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GA...
T4363 CGP52432 139667-74-6 99.16%
CGP52432
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).
T3S2100 (-)-Securinine 5610-40-2 99.12%
(-)-Securinine
(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.
T77568 6,7-dimethylisatin 20205-43-0 99.09%
6,7-dimethylisatin
6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
T23470 Tracazolate hydrochloride 1135210-68-2 99.07%
Tracazolate hydrochloride
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochlori...
T17144 TPA 023 252977-51-8 99.06%
TPA 023
TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).
T0627 β-Alanine 107-95-9 99%
β-Alanine
β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotr...
T0883 Tramiprosate 3687-18-1 99%
Tramiprosate
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble A...
T1602 Valproic acid sodium salt 1069-66-5 99%
Valproic acid sodium salt
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into i...
T2775 Baicalin 21967-41-9 98.96%
Baicalin
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV proper...
T7557 Guvacine hydrochloride 6027-91-4 98.96%
Guvacine hydrochloride
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
T10618 Broflanilide 1207727-04-5 98.95%
Broflanilide
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL ...
T11061 DMCM hydrochloride 1215833-62-7 98.95%
DMCM hydrochloride
DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA αxβ3γ2 receptor sub...
T38205 3-Aminopropylphosphonic Acid 13138-33-5 98.9%
3-Aminopropylphosphonic Acid
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding as...
T23339 SCS 3232-36-8 98.89%
SCS
SCS is a GABAA receptor antagonist.
T11277 FG 7142 78538-74-6 98.81%
FG 7142
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylati...
T22301 L-838417 D9 1213669-91-0 98.81%
L-838417 D9
L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
Etifoxine hydrochloride
T13690
Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug. Unlike benzodiazepines, Etifoxine hydrochloride appears to produce i...
BPDBA
T26891
BPDBA is a useful organic compound for research related to life sciences. The catalog number is T26891 and the CAS number is 312281-74-6.
Tiagabine
T2407
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Acti...
3,4,5-Trimethoxycinnamic acid
T2983
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GA...
CGP52432
T4363
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).
(-)-Securinine
T3S2100
(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.
6,7-dimethylisatin
T77568
6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
Tracazolate hydrochloride
T23470
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochlori...
TPA 023
T17144
TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).
β-Alanine
T0627
β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotr...
Tramiprosate
T0883
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble A...
Valproic acid sodium salt
T1602
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into i...
Baicalin
T2775
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV proper...
Guvacine hydrochloride
T7557
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
Broflanilide
T10618
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL ...
DMCM hydrochloride
T11061
DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA αxβ3γ2 receptor sub...
3-Aminopropylphosphonic Acid
T38205
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding as...
SCS
T23339
SCS is a GABAA receptor antagonist.
FG 7142
T11277
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylati...
L-838417 D9
T22301
L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
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TargetMol