GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
T0508	γ-Aminobutyric acid	56-12-2	98%
T0508	4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.
T7165	Basmisanil	1159600-41-5	98%
T7165	Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of...
T0675	Topiramate	97240-79-4	98%
T0675	Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T15380	Gidazepam	129186-29-4	98%
T15380	Gidazepam is a potent GABA receptor channel (GABA RCs) agonist, a selective derivative of atypical benzodiazepine compounds. Gidazepam has anti-anxiety activity ...
T7136	AZD-6280	942436-93-3	98%
T7136	AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
T23466	TP003	628690-75-5	98%
T23466	TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
T22348	Isonipecotic acid	498-94-2	98%
T22348	Isonipecotic acid is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
T16535	Picrotoxinin	17617-45-7	98%
T16535	Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
T28303	Pazinaclone	103255-66-9	98%
T28303	Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
T3S2259	Methyl eugenol	93-15-2	98%
T3S2259	1. Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcino...
T28887	Suriclone	53813-83-5	98%
T28887	Suriclone is a selective cyclic pyrrolidone analog with sedative and anxiolytic activity, but not significant sedative effects.Suriclone shows its effects by mod...
T7622	Gabazine	104104-50-9	98%
T7622	Gabazine is an antagonist of GABAA receptors (Ki : 74-150 nM)
TN6773	Acetoxyvalerensre	81397-67-3	98%
TN6773	Acetoxyvalerensre (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
T7793	6-(4-Methoxyphenyl)-3-pyridazinamine	4776-87-8	98%
T7793	6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist
T8971	Imidazenil	151271-08-8	98%
T8971	Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.
T4176	Rac-BHFF	123557-91-5	98%
T4176	Rac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectivel...
T14983	Clomethiazole	533-45-9	98%
T14983	Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlorme...
T1860	Imepitoin	188116-07-6	98%
T1860	AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
T8162	Cannabidivarin	24274-48-4	98%
T8162	Cannabidivarin is a potent inhibitor against gamma 2 subunit of GABAA receptors. it may serve as a novel drug with definite control over childhood absence epilep...
T27310	Fengabine	80018-06-0	98%
T27310	Fengabine is a GABA receptor agonist with antidepressant activity and is used to treat depression.