T0508 |
γ-Aminobutyric acid
|
56-12-2
|
98%
|
|
4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.
|
T7165 |
Basmisanil
|
1159600-41-5
|
98%
|
|
Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of...
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
|
T15380 |
Gidazepam
|
129186-29-4
|
98%
|
|
Gidazepam is a potent GABA receptor channel (GABA RCs) agonist, a selective derivative of atypical benzodiazepine compounds. Gidazepam has anti-anxiety activity ...
|
T7136 |
AZD-6280
|
942436-93-3
|
98%
|
|
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
|
T23466 |
TP003
|
628690-75-5
|
98%
|
|
TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
|
T22348 |
Isonipecotic acid
|
498-94-2
|
98%
|
|
Isonipecotic acid is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
|
T16535 |
Picrotoxinin
|
17617-45-7
|
98%
|
|
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
|
T28303 |
Pazinaclone
|
103255-66-9
|
98%
|
|
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
|
T3S2259 |
Methyl eugenol
|
93-15-2
|
98%
|
|
1. Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcino...
|
T28887 |
Suriclone
|
53813-83-5
|
98%
|
|
Suriclone is a selective cyclic pyrrolidone analog with sedative and anxiolytic activity, but not significant sedative effects.Suriclone shows its effects by mod...
|
T7622 |
Gabazine
|
104104-50-9
|
98%
|
|
Gabazine is an antagonist of GABAA receptors (Ki : 74-150 nM)
|
TN6773 |
Acetoxyvalerensre
|
81397-67-3
|
98%
|
|
Acetoxyvalerensre (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
|
T7793 |
6-(4-Methoxyphenyl)-3-pyridazinamine
|
4776-87-8
|
98%
|
|
6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist
|
T8971 |
Imidazenil
|
151271-08-8
|
98%
|
|
Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.
|
T4176 |
Rac-BHFF
|
123557-91-5
|
98%
|
|
Rac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectivel...
|
T14983 |
Clomethiazole
|
533-45-9
|
98%
|
|
Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlorme...
|
T1860 |
Imepitoin
|
188116-07-6
|
98%
|
|
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
|
T8162 |
Cannabidivarin
|
24274-48-4
|
98%
|
|
Cannabidivarin is a potent inhibitor against gamma 2 subunit of GABAA receptors. it may serve as a novel drug with definite control over childhood absence epilep...
|
T27310 |
Fengabine
|
80018-06-0
|
98%
|
|
Fengabine is a GABA receptor agonist with antidepressant activity and is used to treat depression.
|