Home Tools
Log in
Cart

GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.
Cat. No. Product name CAS No. Purity Chemical Structure
T0508 γ-Aminobutyric acid 56-12-2 98%
4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.
T7165 Basmisanil 1159600-41-5 98%
Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of...
T0675 Topiramate 97240-79-4 98%
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T15380 Gidazepam 129186-29-4 98%
Gidazepam is a potent GABA receptor channel (GABA RCs) agonist, a selective derivative of atypical benzodiazepine compounds. Gidazepam has anti-anxiety activity ...
T7136 AZD-6280 942436-93-3 98%
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
T23466 TP003 628690-75-5 98%
TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
T22348 Isonipecotic acid 498-94-2 98%
Isonipecotic acid is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
T16535 Picrotoxinin 17617-45-7 98%
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
T28303 Pazinaclone 103255-66-9 98%
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
T3S2259 Methyl eugenol 93-15-2 98%
1. Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcino...
T28887 Suriclone 53813-83-5 98%
Suriclone is a selective cyclic pyrrolidone analog with sedative and anxiolytic activity, but not significant sedative effects.Suriclone shows its effects by mod...
T7622 Gabazine 104104-50-9 98%
Gabazine is an antagonist of GABAA receptors (Ki : 74-150 nM)
TN6773 Acetoxyvalerensre 81397-67-3 98%
Acetoxyvalerensre (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
T7793 6-(4-Methoxyphenyl)-3-pyridazinamine 4776-87-8 98%
6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist
T8971 Imidazenil 151271-08-8 98%
Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.
T4176 Rac-BHFF 123557-91-5 98%
Rac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectivel...
T14983 Clomethiazole 533-45-9 98%
Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlorme...
T1860 Imepitoin 188116-07-6 98%
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
T8162 Cannabidivarin 24274-48-4 98%
Cannabidivarin is a potent inhibitor against gamma 2 subunit of GABAA receptors. it may serve as a novel drug with definite control over childhood absence epilep...
T27310 Fengabine 80018-06-0 98%
Fengabine is a GABA receptor agonist with antidepressant activity and is used to treat depression.
γ-Aminobutyric acid
T0508
4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.
Basmisanil
T7165
Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of...
Topiramate
T0675
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
Gidazepam
T15380
Gidazepam is a potent GABA receptor channel (GABA RCs) agonist, a selective derivative of atypical benzodiazepine compounds. Gidazepam has anti-anxiety activity ...
AZD-6280
T7136
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
TP003
T23466
TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
Isonipecotic acid
T22348
Isonipecotic acid is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
Picrotoxinin
T16535
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
Pazinaclone
T28303
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
Methyl eugenol
T3S2259
1. Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcino...
Suriclone
T28887
Suriclone is a selective cyclic pyrrolidone analog with sedative and anxiolytic activity, but not significant sedative effects.Suriclone shows its effects by mod...
Gabazine
T7622
Gabazine is an antagonist of GABAA receptors (Ki : 74-150 nM)
Acetoxyvalerensre
TN6773
Acetoxyvalerensre (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
6-(4-Methoxyphenyl)-3-pyridazinamine
T7793
6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist
Imidazenil
T8971
Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.
rac-BHFF
T4176
Rac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectivel...
Clomethiazole
T14983
Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlorme...
Imepitoin
T1860
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
Cannabidivarin
T8162
Cannabidivarin is a potent inhibitor against gamma 2 subunit of GABAA receptors. it may serve as a novel drug with definite control over childhood absence epilep...
Fengabine
T27310
Fengabine is a GABA receptor agonist with antidepressant activity and is used to treat depression.
1 2 3 4 5 6 7 8 9 10