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GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T26834 BL-1020 Mesylate 916898-61-8 100%
BL-1020 Mesylate
BL-1020 Mesylate (CYP-1020 Mesylate) is an orally available GABA A receptor agonist and D2 antagonist that decreases dopamine activity and enhances GABAA activit...
T27845 Losigamone 112856-44-7 100%
Losigamone
Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.
T20657 Muscimol HBr 18174-72-6 100%
Muscimol HBr
Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.
T1673 Acamprosate calcium 77337-73-6
Acamprosate calcium
Acamprosate calcium (Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems, used for treating alcohol dependence.
T12492 Pivagabine 69542-93-4
Pivagabine
Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats...
T5880 Aminooxyacetic acid hemihydrochloride 2921-14-4
Aminooxyacetic acid hemihydrochloride
Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride) is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degrada...
T16539 Piperazine citrate 144-29-6
Piperazine citrate
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmi...
T2998 Dihydromyricetin 27200-12-0
Dihydromyricetin
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase wit...
T16489 Darigabat 1614245-70-3 98%
Darigabat
Darigabat (PF-06372865) is an orally active and selective GABAA receptor modulator that crosses the blood-brain barrier and exhibits anxiolytic activity, with Ki...
T24381 L-822179 215874-86-5 98%
L-822179
L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.
TN1308 6-Hydroxyflavanone 4250-77-5 98%
6-Hydroxyflavanone
6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX...
T4993 Afloqualone 56287-74-2 98%
Afloqualone
Afloqualone (HQ-495) is a agonist of GABA Receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. It has sedative and mu...
T1240 Flumazenil 78755-81-4 98%
Flumazenil
Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous ...
T37190 L-Allylglycine 16338-48-0 98%
L-Allylglycine
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
T32098L Homocarnosine acetate 98%
Homocarnosine acetate
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-infla...
T8268 6,2'-Dihydroxyflavone 92439-20-8 98%
6,2'-Dihydroxyflavone
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
T28479 PZ-II-029 164025-44-9 98%
PZ-II-029
PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.
T21793 CGP 35348 123690-79-9 98%
CGP 35348
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after n...
BL-1020 Mesylate
T26834
BL-1020 Mesylate (CYP-1020 Mesylate) is an orally available GABA A receptor agonist and D2 antagonist that decreases dopamine activity and enhances GABAA activit...
Losigamone
T27845
Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.
Muscimol HBr
T20657
Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.
Acamprosate calcium
T1673
Acamprosate calcium (Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems, used for treating alcohol dependence.
Pivagabine
T12492
Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats...
Aminooxyacetic acid hemihydrochloride
T5880
Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride) is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degrada...
Piperazine citrate
T16539
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmi...
Dihydromyricetin
T2998
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase wit...
Darigabat
T16489
Darigabat (PF-06372865) is an orally active and selective GABAA receptor modulator that crosses the blood-brain barrier and exhibits anxiolytic activity, with Ki...
L-822179
T24381
L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.
6-Hydroxyflavanone
TN1308
6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX...
Afloqualone
T4993
Afloqualone (HQ-495) is a agonist of GABA Receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. It has sedative and mu...
Flumazenil
T1240
Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous ...
L-Allylglycine
T37190
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
Homocarnosine acetate
T32098L
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-infla...
6,2'-Dihydroxyflavone
T8268
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
PZ-II-029
T28479
PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.
CGP 35348
T21793
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after n...
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TargetMol