Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T6078 | Saracatinib | 379231-04-6 | 98.03% |
|
Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes. | ||||
TL0016 | Sulforaphene | 592-95-0 | 98.01% |
|
Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes canc... | ||||
T5675 | Almonertinib hydrochloride | 2134096-03-8 | 98.01% |
|
Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity... | ||||
T9909 | Pertuzumab | 380610-27-5 | 98.00% |
Pertuzumab
|
Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 t... | ||||
T7322 | Theliatinib | 1353644-70-8 | 98% |
|
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR... | ||||
T3506 | Nazartinib | 1508250-71-2 | 98% |
|
Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L... | ||||
T7101 | Tyrphostin AG30 | 122520-79-0 | 98% |
|
Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. | ||||
T6734 | WZ8040 | 1214265-57-2 | 98% |
|
WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I). | ||||
TQ0166 | Tesevatinib | 781613-23-8 | 97.89% |
|
Tesevatinib (XL-647) is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4).... | ||||
T2S0961 | Chalcone | 94-41-7 | 97.89% |
|
Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chal... | ||||
T12542 | Rilzabrutinib | 1575596-29-0 | 97.87% |
|
Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK)(IC50 of 1.3 nM). | ||||
T2630 | Poziotinib | 1092364-38-9 | 97.81% |
|
Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM). | ||||
T7819 | TAS0728 | 2088323-16-2 | 97.78% |
|
TAS0728 is a HER2 inhibitor, with antitumor activity | ||||
T4185 | Lavendustin C | 125697-93-0 | 97.77% |
|
lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase. | ||||
T2032 | WHI-P180 | 211555-08-7 | 97.74% |
|
WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively. | ||||
T75120 | EGFR-IN-76 | 2607829-38-7 | 97.72% |
|
EGFR-IN-76 is a potent EGFR inhibitor. | ||||
T7198 | E-4031 | 113559-13-0 | 97.71% |
|
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM) | ||||
T3466 | FIIN-3 | 1637735-84-2 | 97.7% |
|
FIIN-3 is an irreversible inhibitor of FGFR. | ||||
T3059 | ALK-IN-1 | 1197958-12-5 | 97.66% |
|
ALK-IN-1 (AP26113) is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M ... | ||||
T21312 | Afatinib | 850140-72-6 | 97.56% |
|
Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , ... |