T72784L |
OTUB1/USP8-IN-1 HCl
|
|
99.90%
|
|
OTUB1/USP8-IN-1 HCL is a potent dual inhibitor of OTUB1 and USP8 with potential antitumour activity, inhibiting both OTUB1 and USP8. OTUB1/USP8-IN-1 may be used ...
|
T36970 |
STD1T
|
893075-58-6
|
98.77%
|
|
STD1T is a selective and potent inhibitor of the deubiquitinase USP2a with potential anticancer activity that reduces cell cycle protein D1 protein levels in HCT...
|
T13271 |
USP7-IN-6
|
2166586-47-4
|
98%
|
|
USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).
|
T13270 |
USP7-IN-5
|
2166599-74-0
|
98%
|
|
USP7-IN-5 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 49.9 nM).
|
T12621L |
FT671
|
1959551-26-8
|
98%
|
|
FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).
|
T13269 |
USP7-IN-3
|
2202738-42-7
|
98%
|
|
USP7-IN-3 is a potent and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7).
|
T6300 |
Degrasyn
|
856243-80-6
|
99.98%
|
|
Degrasyn (WP1130) (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (...
|
T1757 |
ML-323
|
1572414-83-5
|
99.96%
|
|
ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (...
|
T4067 |
VLX1570
|
1431280-51-1
|
99.91%
|
|
VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.
|
T22168 |
Vialinin A
|
858134-23-3
|
99.89%
|
|
Vialinin A (Terrestrin A), a p-terphenyl compound, exhibits antioxidant properties and acts as a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific...
|
T6925 |
P005091
|
882257-11-6
|
99.87%
|
|
P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.
|
T74793 |
USP28-IN-3
|
2931509-14-5
|
99.85%
|
|
USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 μM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8...
|
T1862 |
PR-619
|
2645-32-1
|
99.83%
|
|
PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs).
|
T61575 |
USP15-IN-1
|
2260826-16-0
|
99.81%
|
|
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity against non-small cell lung cancer and leukemia cells...
|
T7685 |
USP25/28 inhibitor AZ1
|
2165322-94-9
|
99.79%
|
|
USP25/28 inhibitor AZ1 (AZ1) (AZ1) is an inhibitor of ubiquitin specific protease (USP) 25/28
|
T37591 |
IMP-1710
|
2383117-96-0
|
99.77%
|
|
IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.
|
T11464 |
GRL0617
|
1093070-16-6
|
99.77%
|
|
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
|
T12926 |
SJB3-019A
|
2070015-29-9
|
99.75%
|
|
SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times mor...
|
T3951 |
NSC632839
|
157654-67-6
|
99.74%
|
|
NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2 (...
|
T3555 |
ML364
|
1991986-30-1
|
99.70%
|
|
ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.
|