T0926 |
Azelaic acid
|
123-99-9
|
99.89%
|
|
Azelaic acid (Anchoic acid) is bactericidal against Propionibacterium acnes and Staphylococcus epidermidis due to its inhibitory effect on the synthesis of micro...
|
T6357 |
(S)-crizotinib
|
1374356-45-2
|
99.89%
|
|
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.
|
T9271 |
RAD51-IN-1
|
2101739-18-6
|
99.87%
|
|
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
|
TN1244 |
3'-Demethylnobiletin
|
112448-39-2
|
99.87%
|
|
3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle a...
|
T0717 |
Enoxacin hydrate
|
84294-96-2
|
99.86%
|
|
Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
|
T4226 |
Amenamevir
|
841301-32-4
|
99.86%
|
|
Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL)....
|
T2219 |
Puromycin dihydrochloride
|
58-58-2
|
99.86%
|
|
Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibi...
|
T0676 |
Hydroxyurea
|
127-07-1
|
99.85%
|
|
Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
|
T6069 |
Gemcitabine hydrochloride
|
122111-03-9
|
99.85%
|
|
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a DNA synthesis inhibitor (IC50s: 12, 18, 40, 92.7, 89.3 in Capan2, BxPC-3, Mia Paca-2, PANC-1, and PL-45 ...
|
T6908 |
NSC 228155
|
113104-25-9
|
99.84%
|
|
NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
|
T11020 |
DHODH-IN-11
|
1263303-95-2
|
99.84%
|
|
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.
|
T1724 |
SCR7 pyrazine
|
14892-97-8
|
99.83%
|
|
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
|
T0986 |
Flucytosine
|
2022-85-7
|
99.83%
|
|
Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.
|
T3658 |
Trifluridine/tipiracil hydrochloride mixture
|
733030-01-8
|
99.82%
|
|
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a mola...
|
T0684 |
Ribavirin
|
36791-04-5
|
99.82%
|
|
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
|
T28918 |
Talviraline
|
163451-80-7
|
99.82%
|
|
Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a v...
|
T1153 |
Trimethoprim
|
738-70-5
|
99.81%
|
|
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor...
|
T3103 |
L67
|
325970-71-6
|
99.79%
|
|
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
|
T0125 |
Epirubicin hydrochloride
|
56390-09-1
|
99.79%
|
|
Epirubicin hydrochloride (Pharmorubicin) is an antineoplastic agent which can inhibit Topoisomerase.
|
T60037 |
SR15006
|
2505001-54-5
|
99.78%
|
|
SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
|