T5413 |
ML216
|
1430213-30-1
|
96.83%
|
|
ML-216 is a small molecule inhibitor of BLM helicase (IC50: 1.8 μM). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC...
|
T7525 |
Didox
|
69839-83-4
|
96.85%
|
|
Didox is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients w...
|
T3524 |
Halofuginone hydrobromide
|
64924-67-0
|
97.01%
|
|
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
|
TN2132 |
Quinizarin
|
81-64-1
|
97.02%
|
|
Quinizarin is a natural product
|
T0062 |
Folic acid
|
59-30-3
|
97.02%
|
|
Folic acid(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis.
|
T10104 |
3,4-Dihydroxybenzylamine hydrobromide
|
16290-26-9
|
97.28%
|
|
3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase activity in melanoma cells and displays growth inhibitory activity in melanoma cell lines with vary...
|
T16911 |
Sorivudine
|
77181-69-2
|
97.33%
|
|
Sorivudine is an orally active synthetic pyrimidine nucleoside antimetabolite drug. Sorivudine derives its antiviral activity from selective conversion by a spec...
|
T0681 |
Rifampicin
|
13292-46-1
|
97.36%
|
|
Rifampicin is an antibacterial drug of the class of rifamycin.
|
TN1016 |
Kukoamine A
|
75288-96-9
|
97.45%
|
|
Kukoamine A possesses anticancer, cytoprotective, antioxidant, and anti-inflammatory activities, it also has neuroprotective effects through inhibiting oxidative...
|
T1507 |
Streptozocin
|
18883-66-4
|
97.49%
|
|
Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...
|
T36757 |
DMT-dU-CE Phosphoramidite
|
109389-30-2
|
97.58%
|
|
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.
|
T6856 |
Halofuginone
|
55837-20-2
|
97.67%
|
|
Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mamm...
|
T4228 |
Nolatrexed
|
147149-76-6
|
97.91%
|
|
Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.
|
T6801 |
CeMMEC13
|
1790895-25-8
|
97.95%
|
|
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
|
T7409 |
360A
|
794458-56-3
|
98%
|
|
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
|
T6501 |
Fludarabine Phosphate
|
75607-67-9
|
98%
|
|
Fludarabine Phosphate is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activ...
|
T6456 |
CRT0044876
|
6960-45-8
|
98%
|
|
CRT0044876 is a potent and selective APE1 inhibitor with IC50 of ~3 μM.
|
T7518 |
Deoxycytidine triphosphate trisodium salt
|
109909-44-6
|
98%
|
|
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI Oxidation contributes to antibiotic lethality in stationary-phase mycobacteria.
|
T4356 |
POL1-IN-1
|
1822358-25-7
|
98%
|
|
Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.
|
T1840 |
Isoindigotin
|
476-34-6
|
98%
|
|
Isoindigotin is used in the therapy of Y.
|