T0164 |
Oxaliplatin
|
61825-94-3
|
98%
|
|
Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.
|
T1272 |
Cytarabine
|
147-94-4
|
98%
|
|
Cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterical...
|
T4687 |
Ro5-3335
|
30195-30-3
|
98%
|
|
Ro 5-3335 is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). It represses RUNX1/CBF...
|
T1378 |
Tegafur
|
17902-23-7
|
98%
|
|
Ftorafur is a congener of the antimetabolite fluorouracil with antineoplastic activity. Ftorafur is a prodrug that is gradually converted to fluorouracil in the ...
|
T3279 |
Silver sulfadiazine
|
22199-08-2
|
98%
|
|
Silver Sulfadiazine is a sulfonamide-based topical agent with antibacterial and antifungal activity.
|
T7766 |
Remdesivir
|
1809249-37-3
|
98%
|
|
Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells)
|
T1600 |
Doxifluridine
|
3094-09-5
|
98%
|
|
Doxifluridine is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designe...
|
T0189 |
Pemetrexed
|
137281-23-3
|
98%
|
|
Pemetrexed, a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).
|
T0964 |
Floxuridine
|
50-91-9
|
98%
|
|
Floxuridine is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
|
T3343 |
5-methoxyflavone
|
42079-78-7
|
98%
|
|
5-methoxyflavone is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities.
|
T1703 |
SN-38
|
86639-52-3
|
98%
|
|
SN-38 is an active metabolite of CPT-11.
|
T6069 |
Gemcitabine hydrochloride
|
122111-03-9
|
98%
|
|
Gemcitabine is a DNA synthesis inhibitor (IC50s: 12, 18, 40, 92.7, 89.3 in Capan2, BxPC-3, Mia Paca-2, PANC-1, and PL-45 cells, respectively).
|
T6446 |
Clevudine
|
163252-36-6
|
98%
|
|
Clevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolite...
|
TMA0984 |
Cerevisterol
|
516-37-0
|
98%
|
|
Cerevisterol is a cytotoxic steroid, can inhibit the activity of DNA polymerase alpha. It can stimulate NGF-mediated neurite outgrowth on PC12 cells.
|
TN5153 |
Torilin
|
13018-10-5
|
98%
|
|
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic...
|
TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
|